eF-site ID 2hbh-A
PDB Code 2hbh
Chain A

click to enlarge
Title Crystal structure of Vitamin D nuclear receptor ligand binding domain bound to a locked side-chain analog of calcitriol and SRC-1 peptide
Classification GENE REGULATION
Compound Vitamin D receptor
Source Danio rerio (Zebrafish) (Brachydanio rerio) (NCOA1_HUMAN)
Sequence A:  HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLS
MLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKS
SAIEIIMLRSNQSFSLEDMSWSCGGPDFKYCINDVTKAGH
TLELLEPLVKFQVGLKKLKLHEEEHVLLMAICLLSPDRPG
VQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKL
ADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
Description


Functional site

1) chain A
residue 175
type
sequence Y
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

2) chain A
residue 265
type
sequence S
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

3) chain A
residue 302
type
sequence R
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

4) chain A
residue 303
type
sequence S
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

5) chain A
residue 306
type
sequence S
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

6) chain A
residue 314
type
sequence W
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

7) chain A
residue 316
type
sequence C
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

8) chain A
residue 328
type
sequence V
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

9) chain A
residue 333
type
sequence H
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

10) chain A
residue 423
type
sequence H
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

11) chain A
residue 427
type
sequence Y
description BINDING SITE FOR RESIDUE XE4 A 500
source : AC1

12) chain A
residue 265
type MOD_RES
sequence S
description Phosphoserine => ECO:0007744|PubMed:23186163
source Swiss-Prot : SWS_FT_FI1

13) chain A
residue 302
type MOD_RES
sequence R
description Phosphoserine => ECO:0007744|PubMed:23186163
source Swiss-Prot : SWS_FT_FI1

14) chain A
residue 306
type MOD_RES
sequence S
description Phosphoserine => ECO:0007744|PubMed:23186163
source Swiss-Prot : SWS_FT_FI1

15) chain A
residue 333
type MOD_RES
sequence H
description Phosphoserine => ECO:0007744|PubMed:23186163
source Swiss-Prot : SWS_FT_FI1

16) chain A
residue 423
type MOD_RES
sequence H
description Phosphoserine => ECO:0007744|PubMed:23186163
source Swiss-Prot : SWS_FT_FI1


Display surface

Download
Links