eF-site ID 2h72-AB PDB Code 2h72 Chain A, B click to enlarge Title Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group Classification ELECTRON TRANSPORT Compound Thioredoxin Source (Q2M889_ECOLI) Sequence A:  DKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPI LDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLF KNGDVAATKVGALSKGQLKEFLDANLA B:  SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAP ILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLL FKNGDVAATKVGALSKGQLKEFLDANL Description Functional site 1) chain A residue 73 type sequence R description BINDING SITE FOR RESIDUE MPD A 501 source : AC1 2) chain B residue 31 type sequence W description BINDING SITE FOR RESIDUE MPD A 501 source : AC1 3) chain A residue 19 type sequence A description BINDING SITE FOR RESIDUE MPD A 502 source : AC2 4) chain A residue 22 type sequence A description BINDING SITE FOR RESIDUE MPD A 502 source : AC2 5) chain A residue 53 type sequence L description BINDING SITE FOR RESIDUE MPD A 502 source : AC2 6) chain A residue 54 type sequence T description BINDING SITE FOR RESIDUE MPD A 502 source : AC2 7) chain A residue 69 type MOD_RES sequence K description N6-acetyllysine => ECO:0000269|PubMed:18723842 source Swiss-Prot : SWS_FT_FI4 8) chain B residue 69 type MOD_RES sequence K description N6-acetyllysine => ECO:0000269|PubMed:18723842 source Swiss-Prot : SWS_FT_FI4 9) chain A residue 32 type ACT_SITE sequence C description Nucleophile source Swiss-Prot : SWS_FT_FI1 10) chain A residue 35 type ACT_SITE sequence C description Nucleophile source Swiss-Prot : SWS_FT_FI1 11) chain B residue 32 type ACT_SITE sequence C description Nucleophile source Swiss-Prot : SWS_FT_FI1 12) chain B residue 35 type ACT_SITE sequence C description Nucleophile source Swiss-Prot : SWS_FT_FI1 13) chain A residue 26 type SITE sequence D description Deprotonates C-terminal active site Cys source Swiss-Prot : SWS_FT_FI2 14) chain B residue 26 type SITE sequence D description Deprotonates C-terminal active site Cys source Swiss-Prot : SWS_FT_FI2 15) chain A residue 33 type SITE sequence G description Contributes to redox potential value source Swiss-Prot : SWS_FT_FI3 16) chain A residue 34 type SITE sequence P description Contributes to redox potential value source Swiss-Prot : SWS_FT_FI3 17) chain B residue 33 type SITE sequence G description Contributes to redox potential value source Swiss-Prot : SWS_FT_FI3 18) chain B residue 34 type SITE sequence P description Contributes to redox potential value source Swiss-Prot : SWS_FT_FI3 19) chain A residue 24-42 type prosite sequence LVDFWAEWCGPCKMIAPIL description THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL source prosite : PS00194

Display surface Download Links