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eF-site ID
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2h4m-ABCD |
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PDB Code
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2h4m |
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Chain
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A, B, C, D |
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click to enlarge
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Title
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Karyopherin Beta2/Transportin-M9NLS |
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Classification
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PROTEIN TRANSPORT |
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Compound
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Transportin-1 |
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Source
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Homo sapiens (Human) (ROA1_HUMAN) |
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Sequence
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A: |
KPDEQGLQQILQLLKESQSPDTTIQRTVQQKPDFNNYLIF
VLTKLKSEDEPTRSLSGLILKNNVKFQNFPNGVTDFIKSE
CLNNIGDSSPLIRATVGILITTIASKGELQNWPDLLPKLC
SLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNI
MIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHID
SFIENLFALAGDEEPEVRKNVCRALVMLLEVRMDRLLPHM
HNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLV
RHLPKLIPVLVNGMKYSDIDIILLKTISDWNLRKCSAAAL
DVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGA
IAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLS
RYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSA
FATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYD
AIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDL
FPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQA
MLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLV
ARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVK
PCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEM
QPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCP
QEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISV
NPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQ
VGDENWRRFSDQFPLPLKERLAAFYGV
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| B: |
KPDEQGLQQILQLLKESQSPDTTIQRTVQQKPDFNNYLIF
VLTSEDEPTRSLSGLILKNNFQNFPNGVTDFIKSECLNNI
GDSSPLIRATVGILITTIASKGELQNWPDLLPKLCSLLDS
EDYNTCEGAFGALQKICEDPLNIMIPKFLQFFKHSSPKIR
SHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEV
RKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDEN
VALEACEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMKYS
DIDIILLKTISDWNLRKCSAAALDVLANVYRDELLPHILP
LLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELI
PHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKP
LMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLA
YILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPE
YIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSG
FLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDF
MIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKM
PEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPE
FISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINR
PNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTS
LRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVA
SWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPL
KERLAAFYGV
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| C: |
NNQSSNFGPMKGGNFGGRSSGPY
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| D: |
FGNYNNQSSNFGPMKGGNFGGRSSGPY
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Description
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Functional site
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|
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1)
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chain |
C |
| residue |
285 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine => ECO:0007744|PubMed:23186163
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
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chain |
D |
| residue |
285 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
C |
| residue |
284 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Omega-N-methylarginine => ECO:0007744|PubMed:24129315
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
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chain |
D |
| residue |
284 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Omega-N-methylarginine => ECO:0007744|PubMed:24129315
|
| source |
Swiss-Prot : SWS_FT_FI1
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