|
|
eF-site ID
|
2h1x-ABCD |
|
PDB Code
|
2h1x |
|
Chain
|
A, B, C, D |
|
click to enlarge
|
|
|
Title
|
Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) |
|
Classification
|
HYDROLASE |
|
Compound
|
5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) |
|
Source
|
(Q0P422_BRARE) |
|
|
Sequence
|
A: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
| B: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
| C: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
| D: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
12-27 |
| type |
prosite |
| sequence |
HVLNIAQGVPGANMTI
|
| description |
TRANSTHYRETIN_1 Transthyretin signature 1. HVLNiaqGvPGanMtI
|
| source |
prosite : PS00768
|
|
|
2)
|
chain |
A |
| residue |
31 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
D |
| residue |
31 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
D |
| residue |
71 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
D |
| residue |
116 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
71 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
116 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
B |
| residue |
31 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
B |
| residue |
71 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
B |
| residue |
116 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
C |
| residue |
31 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
12)
|
chain |
C |
| residue |
71 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
13)
|
chain |
C |
| residue |
116 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|