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eF-site ID
|
2h1x-ABCD |
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PDB Code
|
2h1x |
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Chain
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A, B, C, D |
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click to enlarge
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Title
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Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) |
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Classification
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HYDROLASE |
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Compound
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5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) |
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Source
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(Q0P422_BRARE) |
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Sequence
|
A: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
| B: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
| C: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
|
| D: |
SPLSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGI
TNDDGRCPGLITKENFIAGVYKMRFETGKYWDALGETCFY
PYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS
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Description
|
(1) |
5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) (E.C.3.5.2.17)
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Functional site
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|
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1)
|
chain |
A |
| residue |
12-27 |
| type |
prosite |
| ligand |
|
| sequence |
HVLNIAQGVPGANMTI
|
| description |
Transthyretin signature 1. [KH]-[IV]-L-[DN]-x(3)-G-x-P-[AG]-x(2)-[LIVM]-x-[IV]
|
| source |
prosite : PS00768
|
|
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2)
|
chain |
B |
| residue |
12-27 |
| type |
prosite |
| ligand |
|
| sequence |
HVLNIAQGVPGANMTI
|
| description |
Transthyretin signature 1. [KH]-[IV]-L-[DN]-x(3)-G-x-P-[AG]-x(2)-[LIVM]-x-[IV]
|
| source |
prosite : PS00768
|
|
|
3)
|
chain |
C |
| residue |
12-27 |
| type |
prosite |
| ligand |
|
| sequence |
HVLNIAQGVPGANMTI
|
| description |
Transthyretin signature 1. [KH]-[IV]-L-[DN]-x(3)-G-x-P-[AG]-x(2)-[LIVM]-x-[IV]
|
| source |
prosite : PS00768
|
|
|
4)
|
chain |
D |
| residue |
12-27 |
| type |
prosite |
| ligand |
|
| sequence |
HVLNIAQGVPGANMTI
|
| description |
Transthyretin signature 1. [KH]-[IV]-L-[DN]-x(3)-G-x-P-[AG]-x(2)-[LIVM]-x-[IV]
|
| source |
prosite : PS00768
|
|
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