eF-site ID 2h0d-AB PDB Code 2h0d Chain A, B click to enlarge Title Structure of a Bmi-1-Ring1B Polycomb group ubiquitin ligase complex Classification METAL BINDING PROTEIN/LIGASE Compound B lymphoma Mo-MLV insertion region Source Homo sapiens (Human) (RING2_HUMAN) Sequence A:  TRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIV RYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVP GLFKNEMKRRRDFYAAH B:  KTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPIC LDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKL VSKRSLRPDPNFDALISKIY Description Functional site 1) chain A residue 18 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 2) chain A residue 21 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 3) chain A residue 39 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 4) chain A residue 42 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 5) chain A residue 34 type sequence C description BINDING SITE FOR RESIDUE ZN A 202 source : AC2 6) chain A residue 36 type sequence H description BINDING SITE FOR RESIDUE ZN A 202 source : AC2 7) chain A residue 53 type sequence C description BINDING SITE FOR RESIDUE ZN A 202 source : AC2 8) chain A residue 56 type sequence C description BINDING SITE FOR RESIDUE ZN A 202 source : AC2 9) chain B residue 51 type sequence C description BINDING SITE FOR RESIDUE ZN B 203 source : AC3 10) chain B residue 54 type sequence C description BINDING SITE FOR RESIDUE ZN B 203 source : AC3 11) chain B residue 72 type sequence C description BINDING SITE FOR RESIDUE ZN B 203 source : AC3 12) chain B residue 75 type sequence C description BINDING SITE FOR RESIDUE ZN B 203 source : AC3 13) chain B residue 67 type sequence C description BINDING SITE FOR RESIDUE ZN B 204 source : AC4 14) chain B residue 69 type sequence H description BINDING SITE FOR RESIDUE ZN B 204 source : AC4 15) chain B residue 87 type sequence C description BINDING SITE FOR RESIDUE ZN B 204 source : AC4 16) chain B residue 90 type sequence C description BINDING SITE FOR RESIDUE ZN B 204 source : AC4 17) chain B residue 112 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q9CQJ4 source Swiss-Prot : SWS_FT_FI3 18) chain B residue 51-91 type ZN_FING sequence CPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTC R description RING-type => ECO:0000255|PROSITE-ProRule:PRU00175 source Swiss-Prot : SWS_FT_FI1 19) chain B residue 41 type MOD_RES sequence S description Phosphoserine => ECO:0000269|PubMed:25519132 source Swiss-Prot : SWS_FT_FI2 20) chain A residue 34-43 type prosite sequence CLHSFCKTCI description ZF_RING_1 Zinc finger RING-type signature. ClHsFCktCI source prosite : PS00518 21) chain B residue 67-76 type prosite sequence CLHRFCADCI description ZF_RING_1 Zinc finger RING-type signature. ClHsFCktCI source prosite : PS00518

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