eF-site ID 2gy5-A PDB Code 2gy5 Chain A click to enlarge Title Tie2 Ligand-Binding Domain Crystal Structure Classification TRANSFERASE Compound Angiopoietin-1 receptor Source Homo sapiens (Human) (TIE2_HUMAN) Sequence A:  AMDLILINSLPLVSDAETSLTCIASGWRPHEPITIGRDFE ALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFC EGRVRGEAIRIRTMKMRQQASFLPATLTMTVDKGDNVNIS FKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPHAQ PQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPECNH LCTACMNNGVCHEDTGECICPPGFMGRTCEKACELHTFGR TCKERCSGQEGCKSYVFCLPDPYGCSCATGWKGLQCNEAC HPGFYGPDCKLRCSCNNGEMCDRFQGCLCSPGWQGLQCER EGIPRMTPKIVDLPDHIEVNSGKFNPICKASGWPLPTNEE MTLVKPDGTVLHPKDFNHTDHFSVAIFTIHRILPPDSGVW VCSVNTVAGMVEKPFNISVKVLP Description (1)  Angiopoietin-1 receptor (E.C.2.7.10.1) Functional site 1) chain A residue 158 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 2) chain A residue 399 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 3) chain A residue 438 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 4) chain A residue 140 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16732286 source Swiss-Prot : SWS_FT_FI1 5) chain A residue 240-251 type prosite sequence CICPPGFMGRTC description EGF_1 EGF-like domain signature 1. CiCppGfmGRtC source prosite : PS00022 6) chain A residue 287-298 type prosite sequence CSCATGWKGLQC description EGF_1 EGF-like domain signature 1. CiCppGfmGRtC source prosite : PS00022 7) chain A residue 329-340 type prosite sequence CLCSPGWQGLQC description EGF_1 EGF-like domain signature 1. CiCppGfmGRtC source prosite : PS00022 8) chain A residue 240-255 type prosite sequence CICPPGFMGRTCEKAC description EGF_2 EGF-like domain signature 2. CiCppGFmgrtcekaC source prosite : PS01186 9) chain A residue 287-302 type prosite sequence CSCATGWKGLQCNEAC description EGF_2 EGF-like domain signature 2. CiCppGFmgrtcekaC source prosite : PS01186 10) chain A residue 329-340 type prosite sequence CLCSPGWQGLQC description EGF_2 EGF-like domain signature 2. CiCppGFmgrtcekaC source prosite : PS01186

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