eF-site ID 2gvl-AB PDB Code 2gvl Chain A, B click to enlarge Title Crystal Structure of Murine NMPRTase Classification TRANSFERASE Compound Nicotinamide phosphoribosyltransferase Source null (NAMPT_MOUSE) Sequence A:  FNILLATDSYKVTHYKQYPPNTSKVYSYFECREYEETVFY GLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERG WNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPE CYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETS GNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDT VAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKD AFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIV SRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVTENSKG YKLLPPYLRVIQGDGVDINTLQEIVEGXKQKKWSIENVSF GSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVAD PNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHT VFKNGKVTKSYSFDEVRKNAQLNI B:  FNILLATDSYKVTHYKQYPPNTSKVYSYFECREYEETVFY GLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERG WNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPE CYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETS GNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDT VAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKD AFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIV SRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVTENSKG YKLLPPYLRVIQGDGVDINTLQEIVEGXKQKKWSIENVSF GSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVAD PNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHT VFKNGKVTKSYSFDEVRKNAQLNI Description (1)  Nicotinamide phosphoribosyltransferase (E.C.2.4.2.12) Functional site 1) chain B residue 196 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 247 type BINDING sequence H description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 311 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 4) chain A residue 196 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 5) chain A residue 247 type BINDING sequence H description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 311 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 7) chain A residue 188 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P43490 source Swiss-Prot : SWS_FT_FI4 8) chain B residue 188 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P43490 source Swiss-Prot : SWS_FT_FI4 9) chain B residue 472 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P43490 source Swiss-Prot : SWS_FT_FI5 10) chain A residue 472 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P43490 source Swiss-Prot : SWS_FT_FI5 11) chain B residue 219 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI2 12) chain B residue 353 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 13) chain B residue 384 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 14) chain B residue 392 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 15) chain A residue 353 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 16) chain A residue 384 type BINDING sequence G description source Swiss-Prot : SWS_FT_FI2 17) chain A residue 392 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 18) chain A residue 219 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI2

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