eF-site ID 2gfb-ABCDEFGH PDB Code 2gfb Chain A, B, C, D, E, F, G, H click to enlarge Title CRYSTAL STRUCTURE OF A CATALYTIC FAB HAVING ESTERASE-LIKE ACTIVITY Classification IMMUNOGLOBULIN Compound IGG2A CNJ206 FAB (LIGHT CHAIN) Source ORGANISM_COMMON: house mouse; ORGANISM_SCIENTIFIC: Mus musculus; Sequence A:  QIQMTQSPSSLSASLGERVSLTCRASQEISGYLSWLQQKP DGTIKRLIYAASTLDSGVPKRFSGSRSGSDYSLTISSLES EDFADYYCLQYASSPYTFGGGTKLEILRGGAAPTVSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNRNEC B:  DVKLVESGGGLVQPGGSRKLSCAASGFTFSSFGMHWVRQA PEKGLEWVAYISSGSSTIYYADTVKGRFTISRDNPKNTLF LQMTSLRSEDTAMYYCARGDYYGSRGAYWGQGTLVTVSAK TTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWN SGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITC NVAHPASSTKVDKKIEPRG C:  QIQMTQSPSSLSASLGERVSLTCRASQEISGYLSWLQQKP DGTIKRLIYAASTLDSGVPKRFSGSRSGSDYSLTISSLES EDFADYYCLQYASSPYTFGGGTKLEILRGGAAPTVSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNRNEC D:  DVKLVESGGGLVQPGGSRKLSCAASGFTFSSFGMHWVRQA PEKGLEWVAYISSGSSTIYYADTVKGRFTISRDNPKNTLF LQMTSLRSEDTAMYYCARGDYYGSRGAYWGQGTLVTVSAK TTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWN SGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITC NVAHPASSTKVDKKIEPRG E:  QIQMTQSPSSLSASLGERVSLTCRASQEISGYLSWLQQKP DGTIKRLIYAASTLDSGVPKRFSGSRSGSDYSLTISSLES EDFADYYCLQYASSPYTFGGGTKLEILRGGAAPTVSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNRNEC F:  DVKLVESGGGLVQPGGSRKLSCAASGFTFSSFGMHWVRQA PEKGLEWVAYISSGSSTIYYADTVKGRFTISRDNPKNTLF LQMTSLRSEDTAMYYCARGDYYGSRGAYWGQGTLVTVSAK TTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWN SGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITC NVAHPASSTKVDKKIEPRG G:  QIQMTQSPSSLSASLGERVSLTCRASQEISGYLSWLQQKP DGTIKRLIYAASTLDSGVPKRFSGSRSGSDYSLTISSLES EDFADYYCLQYASSPYTFGGGTKLEILRGGAAPTVSIFPP SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT STSPIVKSFNRNEC H:  DVKLVESGGGLVQPGGSRKLSCAASGFTFSSFGMHWVRQA PEKGLEWVAYISSGSSTIYYADTVKGRFTISRDNPKNTLF LQMTSLRSEDTAMYYCARGDYYGSRGAYWGQGTLVTVSAK TTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWN SGSLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITC NVAHPASSTKVDKKIEPRG Description (1)  IGG2A FAB FRAGMENT (CNJ206) Functional site 1) chain A residue 192-198 type prosite sequence YTCEATH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH source prosite : PS00290

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