eF-site ID 2gcz_17-A
PDB Code 2gcz
Model 17
Chain A

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Title Solution Structure of alpha-Conotoxin OmIA
Classification TOXIN
Compound Alpha-conotoxin OmIA
Source (CA1A_CONOM)
Sequence A:  GCCSHPACNVNNPHICGX
Description (1)  alpha-conotoxin OmIA


Functional site

1) chain A
residue 13
type
sequence P
description BINDING SITE FOR RESIDUE NH2 A 18
source : AC1

2) chain A
residue 17
type
sequence G
description BINDING SITE FOR RESIDUE NH2 A 18
source : AC1

3) chain A
residue 2-16
type prosite
sequence CCSHPACNVNNPHIC
description ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCShPACNvnnpHIC
source prosite : PS60014

4) chain A
residue 17
type MOD_RES
sequence G
description Glycine amide => ECO:0000269|PubMed:16678128, ECO:0000269|PubMed:16803900
source Swiss-Prot : SWS_FT_FI2

5) chain A
residue 5
type SITE
sequence H
description Key residue for the high potency for alpha-7 nAChRs => ECO:0000305|PubMed:34955864
source Swiss-Prot : SWS_FT_FI1

6) chain A
residue 10
type SITE
sequence V
description Key residue for the high potency for alpha-7 nAChRs => ECO:0000305|PubMed:34955864
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 11
type SITE
sequence N
description Key residue for the high potency for alpha-7 nAChRs => ECO:0000305|PubMed:34955864
source Swiss-Prot : SWS_FT_FI1


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