eF-site ID 2gbf-B PDB Code 2gbf Chain B click to enlarge Title rat dpp-IV with alkynyl cyanopyrrolidine #1 Classification HYDROLASE Compound Dipeptidyl peptidase 4 Source ORGANISM_COMMON: Norway rat; ORGANISM_SCIENTIFIC: Rattus norvegicus; Sequence B:  RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLF NAEHGNSSIFLENSTFEIFGDSISDYSVSPDRLFVLLEYN YVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGIN DWVYEEEIFGAYSALWWSPNGTFLAYAQFNDTGVPLIEYS FYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRI QNYSVMAICDYDKTTLVWNCPTTQEHIETSATGWCGRFRP AEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQL TDHTNKKCLSCDLNPERCQYYSVSLSKEAKYYQLGCRGPG LPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKAD AAFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINK RLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTP EDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQS AQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS HFLQQCFSLR Description (1)  Dipeptidyl peptidase 4 (EC 3.4.14.5) Functional site 1) chain B residue 148 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 2) chain B residue 217 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 3) chain B residue 686 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 4) chain B residue 631 type ACT_SITE sequence S description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU10084 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 709 type ACT_SITE sequence D description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU10084 source Swiss-Prot : SWS_FT_FI1 6) chain B residue 741 type ACT_SITE sequence H description Charge relay system => ECO:0000255|PROSITE-ProRule:PRU10084 source Swiss-Prot : SWS_FT_FI1 7) chain B residue 83 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16768443 source Swiss-Prot : SWS_FT_FI2 8) chain B residue 90 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16768443 source Swiss-Prot : SWS_FT_FI2 9) chain B residue 227 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16768443 source Swiss-Prot : SWS_FT_FI2 10) chain B residue 319 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16768443 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 521 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16768443 source Swiss-Prot : SWS_FT_FI2

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