eF-site ID 2g9n-B PDB Code 2g9n Chain B click to enlarge Title Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A Classification HYDROLASE Compound Eukaryotic initiation factor 4A-I Source Homo sapiens (Human) (IF4A1_HUMAN) Sequence B:  IESNWNEIVDSFDDMNLSESLLRGIYAYGFEXPSAIQQRA ILPCIXGYDVIAQAQSGTGXTATFAISILQQIELDLXATQ ALVLAPTRELAQQIQXVVMALGDYMGASCHACIGGTNVRA EVQXLQMEAPHIIVGTPGRVFDMLNRRYLSPXYIXMFVLD EADEMLSRGFXDQIYDIFQXLNSNTQVVLLSATMPSDVLE VTXXFMRDPIRILVX Description Functional site 1) chain B residue 76 type BINDING sequence A description BINDING => ECO:0000255|PROSITE-ProRule:PRU00541 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 118 type MOD_RES sequence X description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 3) chain B residue 174 type MOD_RES sequence X description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 4) chain B residue 193 type MOD_RES sequence X description N6-acetyllysine => ECO:0000250|UniProtKB:P60843 source Swiss-Prot : SWS_FT_FI4 5) chain B residue 146 type CROSSLNK sequence X description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI5 6) chain B residue 225 type CROSSLNK sequence X description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI5 7) chain B residue 158 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI3

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