eF-site ID 2g83-B PDB Code 2g83 Chain B click to enlarge Title Structure of activated G-alpha-i1 bound to a nucleotide-state-selective peptide: Minimal determinants for recognizing the active form of a G protein alpha subunit Classification SIGNALING PROTEIN Compound Guanine nucleotide-binding protein G(i), alpha-1 subunit Source null (2G83) Sequence B:  EVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAV VYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAE LAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRI AQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVG GQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNR MHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSP LTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTH FTCATDTKNVQFVFDAVTDVIIK Description Functional site 1) chain B residue 42 type sequence G description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 2) chain B residue 43 type sequence E description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 3) chain B residue 46 type sequence K description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 4) chain B residue 178 type sequence R description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 5) chain B residue 180 type sequence K description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 6) chain B residue 181 type sequence T description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 7) chain B residue 201 type sequence V description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 8) chain B residue 202 type sequence G description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 9) chain B residue 203 type sequence G description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 10) chain B residue 204 type sequence Q description BINDING SITE FOR RESIDUE ALF B 359 source : AC2 11) chain B residue 47 type sequence S description BINDING SITE FOR RESIDUE MG B 358 source : AC4 12) chain B residue 179 type sequence V description BINDING SITE FOR RESIDUE MG B 358 source : AC4 13) chain B residue 181 type sequence T description BINDING SITE FOR RESIDUE MG B 358 source : AC4 14) chain B residue 43 type sequence E description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 15) chain B residue 44 type sequence S description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 16) chain B residue 45 type sequence G description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 17) chain B residue 46 type sequence K description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 18) chain B residue 47 type sequence S description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 19) chain B residue 48 type sequence T description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 20) chain B residue 151 type sequence S description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 21) chain B residue 175 type sequence L description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 22) chain B residue 176 type sequence R description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 23) chain B residue 178 type sequence R description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 24) chain B residue 181 type sequence T description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 25) chain B residue 269 type sequence N description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 26) chain B residue 270 type sequence K description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 27) chain B residue 272 type sequence D description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 28) chain B residue 273 type sequence L description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 29) chain B residue 325 type sequence C description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 30) chain B residue 326 type sequence A description BINDING SITE FOR RESIDUE GDP B 355 source : AC6 31) chain B residue 44 type BINDING sequence S description BINDING => ECO:0000269|PubMed:21115486, ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI1 32) chain B residue 270 type BINDING sequence K description BINDING => ECO:0000269|PubMed:21115486, ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI1 33) chain B residue 48 type BINDING sequence T description BINDING => ECO:0000269|PubMed:18434541, ECO:0000269|PubMed:22383884, ECO:0007744|PDB:3QE0 source Swiss-Prot : SWS_FT_FI2 34) chain B residue 182 type BINDING sequence T description BINDING => ECO:0000269|PubMed:18434541, ECO:0000269|PubMed:22383884, ECO:0007744|PDB:3QE0 source Swiss-Prot : SWS_FT_FI2 35) chain B residue 179 type MOD_RES sequence V description ADP-ribosylarginine; by cholera toxin => ECO:0000250 source Swiss-Prot : SWS_FT_FI7 36) chain B residue 205 type MOD_RES sequence R description Deamidated glutamine; by Photorhabdus PAU_02230 => ECO:0000269|PubMed:24141704 source Swiss-Prot : SWS_FT_FI8 37) chain B residue 152 type BINDING sequence A description BINDING => ECO:0007744|PDB:1KJY, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI3 38) chain B residue 176 type BINDING sequence R description BINDING => ECO:0007744|PDB:1KJY, ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:2XNS, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI4 39) chain B residue 201 type BINDING sequence V description BINDING => ECO:0000269|PubMed:21115486 source Swiss-Prot : SWS_FT_FI5 40) chain B residue 327 type BINDING sequence T description BINDING => ECO:0007744|PDB:1Y3A, ECO:0007744|PDB:2G83, ECO:0007744|PDB:2GTP, ECO:0007744|PDB:2IK8, ECO:0007744|PDB:2OM2, ECO:0007744|PDB:3ONW, ECO:0007744|PDB:3QE0, ECO:0007744|PDB:3QI2, ECO:0007744|PDB:3UMR, ECO:0007744|PDB:3UMS, ECO:0007744|PDB:4G5Q source Swiss-Prot : SWS_FT_FI6

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