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eF-site ID
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2fo1-ABCDE |
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PDB Code
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2fo1 |
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Chain
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A, B, C, D, E |
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click to enlarge
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Title
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Crystal Structure of the CSL-Notch-Mastermind ternary complex bound to DNA |
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Classification
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GENE REGULATION/SIGNALLING PROTEIN/DNA |
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Compound
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5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3' |
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Source
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Caenorhabditis elegans (2FO1) |
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Sequence
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A: |
VQSLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKR
FFCPPPCIYLIGQGWKLKKDRVAQLYKTLKASAIHEQQAT
ELVAYIGIGSDTSERQQLDFSTGKVRHPNIYDYCAAKTLY
ISDSDKRKYFDLNAQFFYGCGMEIGGFVSQRIKVISKPSK
KDCKYLCIASGTKVALFNRLRSQTVSTRYLHVEGNAFHAS
STKWGAFTIHLFDDEDNFAVRDGFVYYGSVVKLVDSVTGI
ALPRLRIRKVDKQQVILDASCSEEPVSQLHKCAFQMIDNE
LVYLCLSHDKIIQHQATAINEHRHQINDGAAWTIISTDKA
EYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGR
DFKPNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQT
HWMFTNRTTGDVEVPISLVRDDGVVYSSGLTFSYKSLER
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| B: |
TTACTGTGGGAAAGA
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| C: |
AATCTTTCCCACAGT
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| D: |
EDEPTIGDLNAFHSGEELHRQRSELARANYEKARPEMIAN
QRAVTAHLFNRYTEDEERKRVEQ
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| E: |
RTRKRRXINASVWXPPXENEESPIKLHTEAAGSYAITEPI
TRESVNIIDPRHNRTVLHWIASNSSAEKSEDLIVHEAKEC
IAAGADVNAXDCDENTPLXLAVLARRRRLVAYLXKAGADP
TIYNKSERSALHQAAANRDFGXXVYXLNSTKLKGDIEELD
RNGXTALXIVAHNEGRDQVASAKLLVEKGAKVDYDGAARK
DSEKYKGRTALHYAAQVSNXPIVKYLVGEKGSNKDKQDED
GKTPIXLAAQEGRIEVVXYLIQQGASVEAVDATDHTARQL
AQANNHHNIVDIFDRCR
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Description
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