eF-site ID 2fl2-B PDB Code 2fl2 Chain B click to enlarge Title crystal structure of KSP in complex with inhibitor 19 Classification CELL CYCLE Compound Kinesin-like protein KIF11 Source Homo sapiens (Human) (KIF11_HUMAN) Sequence B:  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL ADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP RTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKG AAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK IGKLNLVDLAGSENNINQSLLTLGRVITALVERTPHVPYR ESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEY AHRAKNILNK Description Functional site 1) chain B residue 112 type sequence T description BINDING SITE FOR RESIDUE MG B 602 source : AC1 2) chain B residue 24 type sequence R description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 3) chain B residue 26 type sequence R description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 4) chain B residue 27 type sequence P description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 5) chain B residue 106 type sequence Q description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 6) chain B residue 107 type sequence T description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 7) chain B residue 108 type sequence G description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 8) chain B residue 109 type sequence T description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 9) chain B residue 110 type sequence G description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 10) chain B residue 111 type sequence K description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 11) chain B residue 112 type sequence T description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 12) chain B residue 113 type sequence F description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 13) chain B residue 118 type sequence E description BINDING SITE FOR RESIDUE ADP B 600 source : AC4 14) chain B residue 116 type sequence E description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 15) chain B residue 117 type sequence G description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 16) chain B residue 118 type sequence E description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 17) chain B residue 119 type sequence R description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 18) chain B residue 133 type sequence A description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 19) chain B residue 136 type sequence I description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 20) chain B residue 137 type sequence P description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 21) chain B residue 160 type sequence L description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 22) chain B residue 211 type sequence Y description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 23) chain B residue 214 type sequence L description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 24) chain B residue 215 type sequence E description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 25) chain B residue 217 type sequence G description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 26) chain B residue 218 type sequence A description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 27) chain B residue 221 type sequence R description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 28) chain B residue 239 type sequence F description BINDING SITE FOR RESIDUE N4T B 605 source : AC6 29) chain B residue 105 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00283 source Swiss-Prot : SWS_FT_FI1 30) chain B residue 146 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links