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eF-site ID
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2fju-B |
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PDB Code
|
2fju |
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Chain
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B |
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click to enlarge
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Title
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Activated Rac1 bound to its effector phospholipase C beta 2 |
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Classification
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SIGNALING PROTEIN,APOPTOSIS/HYDROLASE |
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Compound
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Ras-related C3 botulinum toxin substrate 1 |
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Source
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Homo sapiens (Human) (PLCB2_HUMAN) |
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Sequence
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B: |
PKVKAYLSQGERFIKWDDETTVASPVILRVDPKGYYLYWT
YQSKEMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFP
DNSFLLKTLTVVSGPDMVDLTFHNFVSYKENVGKAWAEDV
LALVKHPLTANASRSTFLDKILVKLKMQLNSEGKIPVKNF
FQMFPADRKRVEAALSACHLPKGKNDAINPEDFPEPVYKS
FLMSLCPRPEIDEIFTSYMTKEHLTKFINQKQRDQGLIDK
YEPSGQLSPEGMVWFLCGPENSVLAQDKLLLHHDMTQPLN
HYFINSSHNTYLTAGQFSGLSSAEMYRQVLLSGCRCVELD
CWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTS
PYPIILSFENHVDSPRQQAKMAEYCRTIFGDMLLTEPLEK
FPLKPGVPLPSPEDLRGKILIKNKKEESGNLDEEEIKKMQ
SDEGTAGLEVTAYEEMSSLVNYIQPTKFVSFEFSAQKNRS
YVISSFTELKAYDLLSKASVQFVDYNKRQMSRIYPKGTRM
DSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNG
QSGYLLKHEFMRRPTTLSITVISGQFLSERSVRTYVEVEL
FGLPGDPKRRYRTKLSPSTNSINPVWKEEPFVFEKILMPE
LASLRVAVMEEGNKFLGHRIIPINALNSGYHHLCLHSESN
MPLTMPALFIFLEMKD
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Description
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Functional site
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|
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1)
|
chain |
B |
| residue |
328 |
| type |
|
| sequence |
N
|
| description |
BINDING SITE FOR RESIDUE CA B 1000
|
| source |
: AC2
|
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2)
|
chain |
B |
| residue |
357 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE CA B 1000
|
| source |
: AC2
|
|
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3)
|
chain |
B |
| residue |
359 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE CA B 1000
|
| source |
: AC2
|
|
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4)
|
chain |
B |
| residue |
408 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE CA B 1000
|
| source |
: AC2
|
|
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5)
|
chain |
B |
| residue |
327 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU00270
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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6)
|
chain |
B |
| residue |
374 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU00270
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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7)
|
chain |
B |
| residue |
328 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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8)
|
chain |
B |
| residue |
357 |
| type |
BINDING |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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9)
|
chain |
B |
| residue |
359 |
| type |
BINDING |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
10)
|
chain |
B |
| residue |
408 |
| type |
BINDING |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|