eF-site ID 2fim-AB PDB Code 2fim Chain A, B click to enlarge Title Structure of the C-terminal domain of Human Tubby-like protein 1 Classification SIGNALING PROTEIN Compound Tubby related protein 1 Source Homo sapiens (Human) (TULP1_HUMAN) Sequence A:  PREFVLRPAPQGRTVRCRLTRDKYPSYFLHLDTEKKVFLL AGRKRKRSKTANYLISIDPTNNFIGKLRSNLLGNRFTVFD NGQNPQRGYSTNVASLRQELAAVIYERRMTVIIPGMSAEN ERVPIRPRNASDGLLVRWQNKTLESLIELHNKPPVWNDDS GSYTLNFQGRVTQASVKNFQIVHADDPDYIVLQFGRVAED AFTLDYRYPLCALQAFAIALSSFD B:  PREFVLRPAPQGRTVRCRLTRDKKGYPSYFLHLDTEKKVF LLAGRKRKRSKTANYLISIDPFIGKLRSNLLGNRFTVFDN GQNPQRGYSTNVASLRQELAAVIYETNVLGFRGPRRMTVI IPGMSAENERVPIRPRNASDGLLVRWQNKTLESLIELHNK PPVWNDDSGSYTLNFQGRVTQASVKNFQIVHADDPDYIVL QFGRVAEDAFTLDYRYPLCALQAFAIALSSFD Description Functional site 1) chain A residue 249 type sequence G description BINDING SITE FOR RESIDUE 3DP A 1003 source : AC1 2) chain A residue 408 type sequence L description BINDING SITE FOR RESIDUE 3DP A 1003 source : AC1 3) chain A residue 448 type sequence Y description BINDING SITE FOR RESIDUE 3DP A 1003 source : AC1 4) chain A residue 466 type sequence R description BINDING SITE FOR RESIDUE 3DP A 1003 source : AC1 5) chain B residue 321 type sequence L description BINDING SITE FOR RESIDUE 3DP A 1003 source : AC1 6) chain B residue 322 type sequence L description BINDING SITE FOR RESIDUE 3DP A 1003 source : AC1 7) chain A residue 250 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC2 8) chain A residue 251 type sequence T description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC2 9) chain A residue 253 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC2 10) chain B residue 258 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1002 source : AC3 11) chain B residue 455 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1002 source : AC3 12) chain A residue 426-439 type prosite sequence FQGRVTQASVKNFQ description TUB_1 Tub family signature 1. FQGRVTqASVKNFQ source prosite : PS01200

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