|
eF-site ID
|
2fhh-U |
PDB Code
|
2fhh |
Chain
|
U |
|
click to enlarge
|
|
Title
|
Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with a peptidyl boronate inhibitor MLN-273 |
Classification
|
HYDROLASE |
Compound
|
20S proteasome, alpha and beta subunits |
Source
|
(AAK46453) |
|
Sequence
|
U: |
SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPS
RSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGY
AYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEV
AHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANAL
KESYAENASLTDALRIAVAALRAGSLGVASLEVAVLDANR
PRRAFRRITGSALQALLVDQ
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
U |
residue |
84 |
type |
SITE |
sequence |
T
|
description |
Covalent link with the inhibitor MLN-273 => ECO:0000269|PubMed:16468986
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
2)
|
chain |
U |
residue |
178 |
type |
SITE |
sequence |
T
|
description |
Covalent link with the inhibitor MLN-273 => ECO:0000269|PubMed:16468986
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|