eF-site ID 2fhh-K
PDB Code 2fhh
Chain K

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Title Crystal Structure of Mycobacterium Tuberculosis Proteasome in complex with a peptidyl boronate inhibitor MLN-273
Classification HYDROLASE
Compound 20S proteasome, alpha and beta subunits
Source (AAK46453)
Sequence K:  SPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPS
RSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGY
AYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEV
AHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANAL
KESYAENASLTDALRIAVAALRAGSLGVASLEVAVLDANR
PRRAFRRITGSALQALLVDQ
Description


Functional site

1) chain K
residue 84
type SITE
sequence T
description Covalent link with the inhibitor MLN-273 => ECO:0000269|PubMed:16468986
source Swiss-Prot : SWS_FT_FI2

2) chain K
residue 178
type SITE
sequence T
description Covalent link with the inhibitor MLN-273 => ECO:0000269|PubMed:16468986
source Swiss-Prot : SWS_FT_FI2


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