eF-site ID 2ffc-A PDB Code 2ffc Chain A click to enlarge Title Crystal Structure of Plasmodium Vivax Orotidine-Monophosphate-Decarboxyl UMP Bound Classification LYASE Compound orotidine 5-monophosphate decarboxylase Source (2FFC) Sequence A:  NLKIKLQKRRDEVNTCLCIGLDPDEADIKSFMQSEKQNGY QSVKKNLSNSGELFAPQMGGQMLLATPPKEAQEKDEFFYF FNHFCFYIINETKEYALAYKMNFAFYLPYGSLGVDVLKNV FDYLHHLNVPTILDIKMNDIGNTVKHYRKFIFDYLRSDSC TANIYMGTQMLRDICLDEECKRYYSTFVLVKTTNADSHIF QNRLSLDGKEAYVVIAEEVQKMAKQLHLEENGEFVGFVVG ANCYDEIKKIRELFPDCYILAPGVGAQKGDLRKMLCNGYS KNYEKVLINVGRAITKSGSPQQAAREYHQQIKEVLAEL Description Functional site 1) chain A residue 41 type sequence D description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 2) chain A residue 133 type sequence K description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 3) chain A residue 135 type sequence N description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 4) chain A residue 167 type sequence D description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 5) chain A residue 169 type sequence K description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 6) chain A residue 172 type sequence D description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 7) chain A residue 173 type sequence I description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 8) chain A residue 176 type sequence T description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 9) chain A residue 225 type sequence T description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 10) chain A residue 226 type sequence T description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 11) chain A residue 295 type sequence P description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 12) chain A residue 300 type sequence Q description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 13) chain A residue 324 type sequence G description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 14) chain A residue 325 type sequence R description BINDING SITE FOR RESIDUE U5P A 5203 source : AC1 15) chain A residue 164-177 type prosite sequence TILDIKMNDIGNTV description OMPDECASE Orotidine 5'-phosphate decarboxylase active site. TIlDiKmnDIGnTV source prosite : PS00156

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