eF-site ID 2fch-A
PDB Code 2fch
Chain A

click to enlarge
Title Crystal Structure of Thioredoxin Mutant G74S
Classification ELECTRON TRANSPORT
Compound Thioredoxin 1
Source null (THIO_ECOLI)
Sequence A:  DKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPI
LDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRSIPTLLLF
KNGEVAATKVGALSKGQLKEFLDANL
Description


Functional site

1) chain A
residue 70
type
sequence Y
description BINDING SITE FOR RESIDUE MPD E 503
source : AC3

2) chain A
residue 89
type
sequence T
description BINDING SITE FOR RESIDUE MPD E 503
source : AC3

3) chain A
residue 72
type
sequence I
description BINDING SITE FOR RESIDUE MPD A 507
source : AC7

4) chain A
residue 70
type MOD_RES
sequence Y
description N6-acetyllysine => ECO:0000269|PubMed:18723842
source Swiss-Prot : SWS_FT_FI4

5) chain A
residue 24-42
type prosite
sequence LVDFWAEWCGPCKMIAPIL
description THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL
source prosite : PS00194

6) chain A
residue 33
type ACT_SITE
sequence G
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 36
type ACT_SITE
sequence K
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

8) chain A
residue 27
type SITE
sequence F
description Deprotonates C-terminal active site Cys
source Swiss-Prot : SWS_FT_FI2

9) chain A
residue 34
type SITE
sequence P
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

10) chain A
residue 35
type SITE
sequence C
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3


Display surface

Download
Links