eF-site ID 2f6j-C PDB Code 2f6j Chain C click to enlarge Title Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state Classification TRANSCRIPTION Compound bromodomain PHD finger transcription factor Source (2F6J) Sequence C:  KLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL IDEYVCPQCQSTEDAXTVLTPLTEKDYEGLKRVLRSLQAH KXAWPFLEPVDPNDAPDYYGVIKEPXDLATXEERVQRRYY EKLTEFVADXTKIFDNCRYYNPSDSPFYQCAEVLESFFVQ KLKGFK Description (1)  bromodomain PHD finger transcription factor/histone H3 tail (1-15)K4me3 Functional site 1) chain C residue 11 type sequence C description BINDING SITE FOR RESIDUE ZN C 1005 source : AC5 2) chain C residue 13 type sequence C description BINDING SITE FOR RESIDUE ZN C 1005 source : AC5 3) chain C residue 34 type sequence H description BINDING SITE FOR RESIDUE ZN C 1005 source : AC5 4) chain C residue 37 type sequence C description BINDING SITE FOR RESIDUE ZN C 1005 source : AC5 5) chain C residue 26 type sequence C description BINDING SITE FOR RESIDUE ZN C 1006 source : AC6 6) chain C residue 29 type sequence C description BINDING SITE FOR RESIDUE ZN C 1006 source : AC6 7) chain C residue 53 type sequence C description BINDING SITE FOR RESIDUE ZN C 1006 source : AC6 8) chain C residue 56 type sequence C description BINDING SITE FOR RESIDUE ZN C 1006 source : AC6 9) chain C residue 17 type SITE sequence Y description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 10) chain C residue 23 type SITE sequence Y description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 11) chain C residue 32 type SITE sequence W description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 12) chain C residue 10 type SITE sequence Y description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 13) chain C residue 8-59 type ZN_FING sequence KLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL IDEYVCPQCQST description PHD-type 2 => ECO:0000255|PROSITE-ProRule:PRU00146 source Swiss-Prot : SWS_FT_FI1

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