eF-site ID 2f6j-B PDB Code 2f6j Chain B click to enlarge Title Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state Classification TRANSCRIPTION Compound bromodomain PHD finger transcription factor Source (2F6J) Sequence B:  TKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAE LIDEYVCPQCQSTEDAXTVLTPLTEKDYEGLKRVLRSLQA HKXAWPFLEPVDPNDAPDYYGVIKEPXDLATXEERVQRRY YEKLTEFVADXTKIFDNCRYYNPSDSPFYQCAEVLESFFV QKLKGFK Description (1)  bromodomain PHD finger transcription factor/histone H3 tail (1-15)K4me3 Functional site 1) chain B residue 11 type sequence C description BINDING SITE FOR RESIDUE ZN B 1003 source : AC3 2) chain B residue 13 type sequence C description BINDING SITE FOR RESIDUE ZN B 1003 source : AC3 3) chain B residue 34 type sequence H description BINDING SITE FOR RESIDUE ZN B 1003 source : AC3 4) chain B residue 37 type sequence C description BINDING SITE FOR RESIDUE ZN B 1003 source : AC3 5) chain B residue 26 type sequence C description BINDING SITE FOR RESIDUE ZN B 1004 source : AC4 6) chain B residue 29 type sequence C description BINDING SITE FOR RESIDUE ZN B 1004 source : AC4 7) chain B residue 53 type sequence C description BINDING SITE FOR RESIDUE ZN B 1004 source : AC4 8) chain B residue 56 type sequence C description BINDING SITE FOR RESIDUE ZN B 1004 source : AC4 9) chain B residue 8-59 type ZN_FING sequence KLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL IDEYVCPQCQST description PHD-type 2 => ECO:0000255|PROSITE-ProRule:PRU00146 source Swiss-Prot : SWS_FT_FI1 10) chain B residue 10 type SITE sequence Y description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 11) chain B residue 17 type SITE sequence Y description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 12) chain B residue 23 type SITE sequence Y description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2 13) chain B residue 32 type SITE sequence W description Histone H3K4me3 binding source Swiss-Prot : SWS_FT_FI2

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