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eF-site ID
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2f58-HLP |
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PDB Code
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2f58 |
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Chain
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H, L, P |
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click to enlarge
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Title
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IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE) |
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Classification
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IMMUNE SYSTEM |
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Compound
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PROTEIN (IGG1 FAB 58.2 ANTIBODY (LIGHT CHAIN)) |
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Source
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ORGANISM_COMMON: house mouse; ORGANISM_SCIENTIFIC: Mus musculus; |
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Sequence
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H: |
DVQLQQSGPDLVKPSQSLSLTCTVTGYSITSGYSWHWIRQ
FPGNKLEWMGYIHYSAGTNYNPSLKSRISITRDTSKNQFF
LQLNSVTTEDTATYYCAREEAMPYGNQAYYYAMDCWGQGT
TVTVSSAKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFP
EPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSP
RPSETVTCNVAHPASSTKVDKKIVPRDC
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| L: |
DIVLTQSPASLAVSLGQRATISCKASQGVDFDGASFMNWY
QQKPGQPPKLLIFAASTLESGIPARFSGRGSGTDFTLNIH
PVEEEDAATYYCQQSHEDPLTFGAGTKLELKRADAAPTVS
IFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQ
NGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEA
THKTSTSPIVKSFNRA
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| P: |
HIGPGRAFGGG
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Description
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Functional site
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1)
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chain |
P |
| residue |
10 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE ARN P 1
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| source |
: AC1
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2)
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chain |
P |
| residue |
11 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE ARN P 1
|
| source |
: AC1
|
|
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3)
|
chain |
P |
| residue |
315 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ARN P 1
|
| source |
: AC1
|
|
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4)
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chain |
P |
| residue |
316 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE ARN P 1
|
| source |
: AC1
|
|
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5)
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chain |
L |
| residue |
192-198 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
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