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eF-site ID
|
2f16-W |
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PDB Code
|
2f16 |
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Chain
|
W |
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click to enlarge
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Title
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Crystal structure of the yeast 20S proteasome in complex with bortezomib |
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Classification
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HYDROLASE |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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W: |
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
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Description
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Functional site
|
|
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1)
|
chain |
W |
| residue |
114 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE BO2 V 1401
|
| source |
: AC4
|
|
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2)
|
chain |
W |
| residue |
118 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE BO2 V 1401
|
| source |
: AC4
|
|
|
3)
|
chain |
W |
| residue |
62 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
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