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eF-site ID
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2f16-I |
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PDB Code
|
2f16 |
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Chain
|
I |
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click to enlarge
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Title
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Crystal structure of the yeast 20S proteasome in complex with bortezomib |
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Classification
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HYDROLASE |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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I: |
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
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Description
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Functional site
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1)
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chain |
I |
| residue |
114 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE BO2 H 1400
|
| source |
: AC1
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2)
|
chain |
I |
| residue |
118 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE BO2 H 1400
|
| source |
: AC1
|
|
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3)
|
chain |
I |
| residue |
4-51 |
| type |
prosite |
| sequence |
VAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLG
ITGLATD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkGknCVVLGCErrstlklqdtritps.KvskidshvvlsfsGlnAD
|
| source |
prosite : PS00854
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