eF-site ID 2esl-C PDB Code 2esl Chain C click to enlarge Title Human Cyclophilin C in Complex with Cyclosporin A Classification ISOMERASE/IMMUNOSUPPRESSANT Compound Peptidyl-prolyl cis-trans isomerase C Source Homo sapiens (Human) (NOR00033) Sequence C:  RGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFV ALATGEKGYGYKGSKFHRVIKDFMIQGGDITTGDGTGGVS IYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLT KPTWLDGKHVVFGKVIDGMTVVHSIELQATDGHDRPLTNC SIINSGKIDVKTPFVVEIADW Description (1)  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C (E.C.5.2.1.8), CYCLOSPORIN A Functional site 1) chain C residue 93 type sequence D description BINDING SITE FOR RESIDUE CA A 1 source : AC1 2) chain C residue 174 type sequence H description BINDING SITE FOR RESIDUE ZN A 4 source : AC4 3) chain C residue 179 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 7 source : AC7 4) chain C residue 180 type sequence A description BINDING SITE FOR RESIDUE SO4 B 7 source : AC7 5) chain C residue 168 type sequence D description BINDING SITE FOR RESIDUE SO4 C 8 source : AC8 6) chain C residue 169 type sequence G description BINDING SITE FOR RESIDUE SO4 C 8 source : AC8 7) chain C residue 170 type sequence M description BINDING SITE FOR RESIDUE SO4 C 8 source : AC8 8) chain C residue 89 type sequence R description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 9) chain C residue 94 type sequence F description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 10) chain C residue 97 type sequence Q description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 11) chain C residue 106 type sequence G description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 12) chain C residue 135 type sequence A description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 13) chain C residue 136 type sequence N description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 14) chain C residue 137 type sequence A description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 15) chain C residue 145 type sequence Q description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 16) chain C residue 147 type sequence F description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 17) chain C residue 155 type sequence W description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 18) chain C residue 160 type sequence H description BINDING SITE FOR CHAIN K OF CYCLOSPORIN A source : BC5 19) chain C residue 137 type sequence A description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : BC8 20) chain C residue 155 type sequence W description BINDING SITE FOR CHAIN N OF CYCLOSPORIN A source : BC8

Display surface Download Links