|
|
eF-site ID
|
2eh7-HL |
|
PDB Code
|
2eh7 |
|
Chain
|
H, L |
|
click to enlarge
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Title
|
Crystal structure of humanized KR127 FAB |
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Classification
|
IMMUNE SYSTEM |
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Compound
|
HUMANIZED KR127 FAB, LIGHT CHAIN |
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Source
|
(2EH7) |
|
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Sequence
|
H: |
QVQLVQSGAEVVKPGASVKVSCKASGYAFSSSWMNWVRQA
PGQGLEWIGRIYPGDGDTNYAQKFQGKATLTADKSTSTAY
MELSSLRSEDTAVYFCAREYDEAYWGQGTLVTVSSASTKG
PSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGA
LTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNV
NHKPSNTKVDKKVEPKSC
|
| L: |
DIQMTQTPLSLSVTPGQPASISCKSSQSLLYSNGKTYLNW
LLQKPGQSPKRLIYLVSKLDSGVPDRFSGSGSGTDFTLKI
SRVEAEDVGVYYCVQGTHFPQTFGGGTKVEIKRTVAAPSV
FIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQ
SGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACE
VTHQGLSSPVTKSFNRGEC
|
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Description
|
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Functional site
|
|
|
1)
|
chain |
L |
| residue |
18-41 |
| type |
prosite |
| sequence |
PASISCKSSQSLLYSNGKTYLNWLLQKPG
|
| description |
ADH_SHORT Short-chain dehydrogenases/reductases family signature. PasisckssqSllYSNGKTYLnWLLqKPG
|
| source |
prosite : PS00061
|
|
|
2)
|
chain |
L |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
3)
|
chain |
H |
| residue |
194-200 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
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|
|