eF-site ID 2e6w-A PDB Code 2e6w Chain A click to enlarge Title Solution structure and calcium binding properties of EF-hands 3 and 4 of calsenilin Classification METAL BINDING PROTEIN Compound Calsenilin Source Homo sapiens (Human) (CSEN_HUMAN) Sequence A:  GTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGR HTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQ KDENIMSSMQLFENVI Description Functional site 1) chain A residue 175 type sequence D description BINDING SITE FOR RESIDUE CA A 300 source : AC1 2) chain A residue 177 type sequence N description BINDING SITE FOR RESIDUE CA A 300 source : AC1 3) chain A residue 179 type sequence D description BINDING SITE FOR RESIDUE CA A 300 source : AC1 4) chain A residue 181 type sequence Y description BINDING SITE FOR RESIDUE CA A 300 source : AC1 5) chain A residue 186 type sequence E description BINDING SITE FOR RESIDUE CA A 300 source : AC1 6) chain A residue 223 type sequence D description BINDING SITE FOR RESIDUE CA A 301 source : AC2 7) chain A residue 225 type sequence N description BINDING SITE FOR RESIDUE CA A 301 source : AC2 8) chain A residue 227 type sequence D description BINDING SITE FOR RESIDUE CA A 301 source : AC2 9) chain A residue 229 type sequence V description BINDING SITE FOR RESIDUE CA A 301 source : AC2 10) chain A residue 231 type sequence T description BINDING SITE FOR RESIDUE CA A 301 source : AC2 11) chain A residue 234 type sequence E description BINDING SITE FOR RESIDUE CA A 301 source : AC2 12) chain A residue 175-187 type prosite sequence DINKDGYITKEEM description EF_HAND_1 EF-hand calcium-binding domain. DINKDGYITkeEM source prosite : PS00018 13) chain A residue 223-235 type prosite sequence DRNQDGVVTIEEF description EF_HAND_1 EF-hand calcium-binding domain. DINKDGYITkeEM source prosite : PS00018

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