eF-site ID 2e2j-B PDB Code 2e2j Chain B click to enlarge Title RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP Classification TRANSCRIPTION,TRANSFERASE/DNA-RNA HYBRID Compound 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3' Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence B:  DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL QDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQEA RLRNLTYSSGLFVDVKKKVFIGRLPIMLRSKNCYLSEATE SDLYKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVF KKAAPSPISHVAEIRSALEKGSRFISTLQVKLYGREGSSA RTIKATLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVN DWQMLEMLKPCVEDGFVIQDRETALDFIGKEKRIQYAKDI LQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQ DDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRT VELAINAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVL NRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPE GQACGLVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDY VPHQSPDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDI NPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHK ELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEE ESILIAMQPEDLEPAEADVDPAKRIRVSHHATTFTHCEIH PSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTN YNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAI VAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEK KYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVR VSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLVTTN QDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITYRRE DMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVAAL SGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYNGHT GKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPMQVLTRQ PVEGRSRDGGLRFGEMERDCMIAHGAASFLKERLMEASDA FRVHICGICGLMTVIAKLNHNQFECKGCDNKIDIYQIHIP YAAKLLFQELMAMNITPRLYTDRSR Description Functional site 1) chain B residue 1163 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 2) chain B residue 1166 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 3) chain B residue 1182 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 4) chain B residue 1185 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 5) chain B residue 837 type sequence D description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 6) chain B residue 766 type sequence R description BINDING SITE FOR RESIDUE G2P T 3000 source : BC2 7) chain B residue 1020 type sequence R description BINDING SITE FOR RESIDUE G2P T 3000 source : BC2 8) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166 9) chain B residue 1185 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI2 10) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1

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