eF-site ID 2e2j-A PDB Code 2e2j Chain A click to enlarge Title RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP Classification TRANSCRIPTION,TRANSFERASE/DNA-RNA HYBRID Compound 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3' Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence A:  GQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETMD ETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHFG HIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNELM RQALAIKDSKKRFAAIWTLCKTKMVCETDVPSLVSRGGCG NTQPTIRKDGLKLVGSWKLRVLSTEEILNIFKHISVKDFT SLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGED DLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFHV ATYMDNDIAGQPQALQKSGRPVKSIRARLKGKEGRIRGNL MGKRVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVV TPYNIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKR AGDIQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRV KVIPYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAE LSQLCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTF IELDQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSV AIPNGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKK TVGSSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHN GFSTGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQAN LLTAKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDL NNVKQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFV DRTLPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGG REGLIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSL GNVIQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVD LLNTDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDR KFLREVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSD LTIKDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCC LLRSRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHP GEMVGVLAAQSIGEPATQMTLKKVTSGVPRLKEILNVAKN MKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTLKSVTIAS EIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLLRLELDRA AMNDKDLTMGQVGERIKQTFKNDLFVIWSEDNDEKLIIRC RVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKYDRK VPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRIYTN SFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRHMAL LVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVEILF EAGASAELDDCRGVSENVILGQMAPIGTGAFDVMI Description Functional site 1) chain A residue 107 type sequence C description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 2) chain A residue 110 type sequence C description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 3) chain A residue 148 type sequence C description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 4) chain A residue 167 type sequence C description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 5) chain A residue 67 type sequence C description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 6) chain A residue 70 type sequence C description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 7) chain A residue 77 type sequence C description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 8) chain A residue 80 type sequence H description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 9) chain A residue 481 type sequence D description BINDING SITE FOR RESIDUE MG A 2001 source : AC9 10) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE MG A 2001 source : AC9 11) chain A residue 485 type sequence D description BINDING SITE FOR RESIDUE MG A 2001 source : AC9 12) chain A residue 481 type sequence D description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 13) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 14) chain A residue 446 type sequence R description BINDING SITE FOR RESIDUE G2P T 3000 source : BC2 15) chain A residue 448 type sequence P description BINDING SITE FOR RESIDUE G2P T 3000 source : BC2 16) chain A residue 479 type sequence N description BINDING SITE FOR RESIDUE G2P T 3000 source : BC2 17) chain A residue 483 type catalytic sequence D description 788 source MCSA : MCSA1 18) chain A residue 485 type catalytic sequence D description 788 source MCSA : MCSA1 19) chain A residue 483 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 20) chain A residue 485 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 21) chain A residue 107 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI1 22) chain A residue 110 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI1 23) chain A residue 148 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI1 24) chain A residue 167 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI1 25) chain A residue 481 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 26) chain A residue 1350 type MOD_RES sequence K description Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI3

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