eF-site ID 2e2h-B PDB Code 2e2h Chain B click to enlarge Title RNA polymerase II elongation complex at 5 mM Mg2+ with GTP Classification TRANSCRIPTION,TRANSFERASE/DNA-RNA HYBRID Compound 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3' Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence B:  DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL QDIICEDSTLIISFGKIYVTKPMVNESDGVTHALYPQEAR LRNLTYSSGLFVDVKVFIGRLPIMLRSKNCYLSEATESDL YKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKA APSPISHVAEIRSALEKGSISTLQVKLYGREGSSARTIKA TLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQML EMLKPCVEDGFVIQDRETALDFIGKEKRIQYAKDILQKEF LPHITQLEGFESRKAFFLGYMINRLLLCALDRKDQDDRDH FGKKRLDLAGPLLAQLFKTLFKKLTKDIFRYMQRTVELAI NAKTITSGLKYALATGNWGEQKKAMSSRAGVSQVLNRYTY SSTLSHLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACG LVKNLSLMSCISVGTDPMPIITFLSEWGMEPLEDYVPHQS PDATRVFVNGVWHGVHRNPARLMETLRTLRRKGDINPEVS MIRDIREKELKIFTDAGRVYRPLFIVEDDESLGHKELKVR KGHIAKLMATEYQDEYTWSSLLNEGLVEYIDAEEEESILI AMQPEDLEPAEDVDPAKRIRVSATTFTHCEIHPSMILGVA ASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTM ANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVAIACYSG YNQEDSMIMNQSSIDRGLFRSLFFRSYMDQEKKYGMSITE TFEKPQRTNTLRMKHGTYDKLDDDGLIAPGVRVSGEDVII GKTTPISRDASTPLRSTENGIVDQVLVTTNQDGLKFVKVR VRTTKIPQIGDKFASRHGQKGTIGITYRREDMPFTAEGIV PDLIINPHAIPSRMTVAHLIECLLSKVAALSGNEGDASPF TDITVEGISKLLREHGYQSRGFEVMYNGHTGKKLMAQIFF GPTYYQRLRHMVDDKIHARARGPMQVLTRQPVEGRSRDGG LRFGEMERDCMIAHGAASFLKERLMEASDAFRVHICGICG LMTVIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQEL MAMNITPRLYTDRSRD Description Functional site 1) chain B residue 1163 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 2) chain B residue 1166 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 3) chain B residue 1182 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 4) chain B residue 1185 type sequence C description BINDING SITE FOR RESIDUE ZN B 1307 source : AC3 5) chain B residue 837 type sequence D description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 6) chain B residue 1020 type sequence R description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 7) chain B residue 766 type sequence R description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 8) chain B residue 987 type sequence K description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 9) chain B residue 1020 type sequence R description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 10) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1 11) chain B residue 1185 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI2 12) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166

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