eF-site ID 2e2h-A PDB Code 2e2h Chain A click to enlarge Title RNA polymerase II elongation complex at 5 mM Mg2+ with GTP Classification TRANSCRIPTION,TRANSFERASE/DNA-RNA HYBRID Compound 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3' Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence A:  VGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETM DETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHF GHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNEL MRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSELVSRGG CGNTQPTIRKDGLKLVGSWLRVLSTEEILNIFKHISVKDF TSLGFNEVFSRPEWMILTCLPVPPPPVRPSISFNESQRGE DDLTFKLADILKANISLETLEHNGAPHHAIEEAESLLQFH VATYMDNDIAGQPQAGRPVKSIRARLKGKEGRIRGNLMGK RVDFSARTVISGDPNLELDQVGVPKSIAKTLTYPEVVTPY NIDRLTQLVRNGPNEHPGAKYVIRDSGDRIDLRYSKRAGD IQLQYGWKVERHIMDNDPVLFNRQPSLHKMSMMAHRVKVI PYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQ LCAVPLQIVSPQSNKPCMGIVQDTLCGIRKLTLRDTFIEL DQVLNMLYWVPDWDGVIPTPAIIKPKPLWSGKQILSVAIP NGIHLQRFDEGTTLLSPKDNGMLIIDGQIIFGVVEKKTVG SSNGGLIHVVTREKGPQVCAKLFGNIQKVVNFWLLHNGFS TGIGDTIADGPTMREITETIAEAKKKVLDVTKEAQANLLT AKHGMTLRESFEDNVVRFLNEARDKAGRLAEVNLKDLNNV KQMVMAGSKGSFINIAQMSACVGQQSVEGKRIAFGFVDRT LPHFSKDDYSPESKGFVENSYLRGLTPQEFFFHAMGGREG LIDTAVKTAETGYIQRRLVKALEDIMVHYDNTTRNSLGNV IQFIYGEDGMDAAHIEKQSLDTIGGSDAAFEKRYRVDLLN TDHTLDPSLLESGSEILGDLKLQVLLDEEYKQLVKDRKFL REVFVDGEANWPLPVNIRRIIQNAQQTFHIDHTKPSDLTI KDIVLGVKDLQENLLVLRGKNEIIQNAQRDAVTLFCCLLR SRLATRRVLQEYRLTKQAFDWVLSNIEAQFLRSVVHPGEM VGVLAAQSIGEPATQMTLNTFHFAGVASKKVTSGVPRLKE ILNVAKNMKTPSLTVYLEPGHAADQEQAKLIRSAIEHTTL KSVTIASEIYYDPDPRSTVIPEDEEIIQLHFSLQQSPWLL RLELDRAAMNDKDLTMGQVGERIKQTFKNDLFVIWSEDLI IRCRVVAEEDHMLKKIENTMLENITLRGVENIERVVMMKY DRKVPSPTGEYVKEPEWVLETDGVNLSEVMTVPGIDPTRI YTNSFIDIMEVLGIEAGRAALYKEVYNVIASDGSYVNYRH MALLVDVMTTQGGLTSVTRHGFNRSNTGALMRCSFEETVE ILFEAGASAELDDCRGVSENVILGQMAPIGTGAFDVMI Description Functional site 1) chain A residue 108 type sequence M description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 2) chain A residue 110 type sequence C description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 3) chain A residue 167 type sequence C description BINDING SITE FOR RESIDUE ZN A 1734 source : AC1 4) chain A residue 67 type sequence C description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 5) chain A residue 70 type sequence C description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 6) chain A residue 77 type sequence C description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 7) chain A residue 80 type sequence H description BINDING SITE FOR RESIDUE ZN A 1735 source : AC2 8) chain A residue 481 type sequence D description BINDING SITE FOR RESIDUE MG A 2001 source : AC9 9) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE MG A 2001 source : AC9 10) chain A residue 485 type sequence D description BINDING SITE FOR RESIDUE MG A 2001 source : AC9 11) chain A residue 481 type sequence D description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 12) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE MG A 2002 source : BC1 13) chain A residue 448 type sequence P description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 14) chain A residue 481 type sequence D description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 15) chain A residue 483 type sequence D description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 16) chain A residue 485 type sequence D description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 17) chain A residue 827 type sequence T description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 18) chain A residue 1081 type sequence L description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 19) chain A residue 1085 type sequence H description BINDING SITE FOR RESIDUE GTP T 3000 source : BC2 20) chain A residue 483 type catalytic sequence D description 788 source MCSA : MCSA1 21) chain A residue 485 type catalytic sequence D description 788 source MCSA : MCSA1 22) chain A residue 1085 type catalytic sequence H description 788 source MCSA : MCSA1 23) chain A residue 483 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1 24) chain A residue 485 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1 25) chain A residue 107 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 26) chain A residue 110 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 27) chain A residue 148 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 28) chain A residue 167 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 29) chain A residue 481 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1

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