eF-site ID 2dga-A PDB Code 2dga Chain A click to enlarge Title Crystal structure of hexameric beta-glucosidase in wheat Classification HYDROLASE Compound Beta-glucosidase Source Triticum aestivum (Wheat) (Q1XH05_WHEAT) Sequence A:  GPVFTKLKPWQIPKRDWFDKDFLFGASTSAYQIEGAWNED GKGPSTWDHFCHTYPERISDMTNGDVAANSYHLYEEDVKA LKDMGMKVYRFSISWSRILPDGTGKVNQAGIDYYNKLINS LIDNDIVPYVTIWHWDTPQALEDKYGGFLNRQIVDDYKQF AEVCFKNFGDRVKNWFTFNEPHTYCCFSYGEGIHAPGRCS PGMDCAVPEGDSLREPYTAGHHILLAHAEAVQLFKARYNM HGDSKIGMAFDVMGYEPYQDSFLDDQARERSIDYNMGWFL EPVVRGDYPFSMRSLIGDRLPMFTKEEQEKLASSCDIMGL NYYTSRFSKHVDMSPDFTPTLNTDDAYASSETTGSDGNDI GPITGTYWIYMYPKGLTDLLLIMKEKYGNPPVFITENGIA DVEGDESMPDPLDDWKRLDYLQRHISAVKDAIDQGADVRG HFTWGLIDNFEWSLGYSSRFGLVYIDKNDGNKRKLKKSAK WFSKFNSVPKP Description Functional site 1) chain A residue 270 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC1 2) chain A residue 271 type sequence D description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC1 3) chain A residue 366 type sequence S description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC1 4) chain A residue 434 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1001 source : AC1 5) chain A residue 191 type sequence E description BINDING SITE FOR RESIDUE GOL A 1314 source : AC2 6) chain A residue 262 type sequence D description BINDING SITE FOR RESIDUE GOL A 1314 source : AC2 7) chain A residue 332 type sequence N description BINDING SITE FOR RESIDUE GOL A 1314 source : AC2 8) chain A residue 334 type sequence Y description BINDING SITE FOR RESIDUE GOL A 1314 source : AC2 9) chain A residue 379 type sequence W description BINDING SITE FOR RESIDUE GOL A 1314 source : AC2 10) chain A residue 43 type sequence Q description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 11) chain A residue 191 type sequence E description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 12) chain A residue 334 type sequence Y description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 13) chain A residue 379 type sequence W description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 14) chain A residue 407 type sequence E description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 15) chain A residue 455 type sequence W description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 16) chain A residue 462 type sequence E description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 17) chain A residue 463 type sequence W description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 18) chain A residue 471 type sequence F description BINDING SITE FOR RESIDUE GOL A 1315 source : AC3 19) chain A residue 205 type sequence H description BINDING SITE FOR RESIDUE GOL A 1316 source : AC4 20) chain A residue 462 type sequence E description BINDING SITE FOR RESIDUE GOL A 1316 source : AC4 21) chain A residue 463 type sequence W description BINDING SITE FOR RESIDUE GOL A 1316 source : AC4 22) chain A residue 464 type sequence S description BINDING SITE FOR RESIDUE GOL A 1316 source : AC4 23) chain A residue 145 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:Q8L7J2 source Swiss-Prot : SWS_FT_FI4 24) chain A residue 334 type BINDING sequence Y description BINDING => ECO:0000250|UniProtKB:Q8L7J2 source Swiss-Prot : SWS_FT_FI4 25) chain A residue 190 type BINDING sequence N description BINDING => ECO:0000305|PubMed:21421370, ECO:0007744|PDB:3AIR source Swiss-Prot : SWS_FT_FI5 26) chain A residue 407 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q9SPP9 source Swiss-Prot : SWS_FT_FI6 27) chain A residue 455 type BINDING sequence W description BINDING => ECO:0000305|PubMed:21421370, ECO:0007744|PDB:3AIS source Swiss-Prot : SWS_FT_FI7 28) chain A residue 471 type BINDING sequence F description BINDING => ECO:0000305|PubMed:21421370, ECO:0007744|PDB:3AIS source Swiss-Prot : SWS_FT_FI7 29) chain A residue 191 type ACT_SITE sequence E description Proton donor => ECO:0000250|UniProtKB:Q8L7J2 source Swiss-Prot : SWS_FT_FI1 30) chain A residue 407 type ACT_SITE sequence E description Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10055 source Swiss-Prot : SWS_FT_FI2 31) chain A residue 403-411 type prosite sequence VFITENGIA description GLYCOSYL_HYDROL_F1_1 Glycosyl hydrolases family 1 active site. VFITENGIA source prosite : PS00572 32) chain A residue 33-47 type prosite sequence FLFGASTSAYQIEGA description GLYCOSYL_HYDROL_F1_2 Glycosyl hydrolases family 1 N-terminal signature. FlFGaStSAYQiEgA source prosite : PS00653 33) chain A residue 43 type BINDING sequence Q description BINDING => ECO:0000305|PubMed:21421370, ECO:0007744|PDB:3AIR, ECO:0007744|PDB:3AIS source Swiss-Prot : SWS_FT_FI3 34) chain A residue 462 type BINDING sequence E description BINDING => ECO:0000305|PubMed:21421370, ECO:0007744|PDB:3AIR, ECO:0007744|PDB:3AIS source Swiss-Prot : SWS_FT_FI3

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