eF-site ID 2d4v-D PDB Code 2d4v Chain D click to enlarge Title Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans Classification OXIDOREDUCTASE Compound isocitrate dehydrogenase Source Thiobacillus thiooxidans (Q8GAX0_THITH) Sequence D:  THIQKPATGSPLTLLNGVLQVPDQPIIPFIEGDGIGCDVT PAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQ YLPDETMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQDL DLYVCLRPVRYFEGTPSPMRHPEKVDMVIFRENSEDIYAG IEWPAGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVS TEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFR DWGYALAEREFAGRVFTWRQKAAISKAEGKAAGQKAEQQA IADGKLIIKDVIADNFLQQILLRPEDYSVVATLNLNGDYV SDALAAEVGGIGMAPGANLSDTHAIFEATHGTAPDIAGQG KANPSSLILSAVMMLEHLGWGEAAQAIVAAMNATIAAGEV TGDLAALRGDVPALSTTEFTAALIRRF Description Functional site 1) chain D residue 230 type sequence K description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 2) chain D residue 232 type sequence N description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 3) chain D residue 233 type sequence I description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 4) chain D residue 296 type sequence D description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 5) chain D residue 105 type sequence T description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 6) chain D residue 113 type sequence S description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 7) chain D residue 115 type sequence N description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 8) chain D residue 119 type sequence R description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 9) chain D residue 129 type sequence R description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 10) chain D residue 153 type sequence R description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 11) chain D residue 160 type sequence Y description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 12) chain D residue 320 type sequence D description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 13) chain D residue 232 type sequence N description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 14) chain D residue 294 type sequence I description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 15) chain D residue 297 type sequence N description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 16) chain D residue 300 type sequence Q description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 17) chain D residue 37 type sequence I description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 18) chain D residue 100 type sequence K description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 19) chain D residue 102 type sequence P description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 20) chain D residue 103 type sequence L description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 21) chain D residue 104 type sequence E description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 22) chain D residue 105 type sequence T description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 23) chain D residue 115 type sequence N description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 24) chain D residue 333 type sequence I description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 25) chain D residue 349 type sequence E description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 26) chain D residue 351 type sequence T description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 27) chain D residue 352 type sequence H description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 28) chain D residue 353 type sequence G description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 29) chain D residue 354 type sequence T description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 30) chain D residue 355 type sequence A description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 31) chain D residue 357 type sequence D description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 32) chain D residue 364 type sequence A description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 33) chain D residue 365 type sequence N description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 34) chain D residue 405 type sequence D description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8

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