eF-site ID 2d4v-C PDB Code 2d4v Chain C click to enlarge Title Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans Classification OXIDOREDUCTASE Compound isocitrate dehydrogenase Source Thiobacillus thiooxidans (Q8GAX0_THITH) Sequence C:  THIQKPATGSPLTLLNGVLQVPDQPIIPFIEGDGIGCDVT PAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQ YLPDETMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQDL DLYVCLRPVRYFEGTPSPMRHPEKVDMVIFRENSEDIYAG IEWPAGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVS TEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFR DWGYALAEREFAGRVFTWRQKAAISKAEGKAAGQKAEQQA IADGKLIIKDVIADNFLQQILLRPEDYSVVATLNLNGDYV SDALAAEVGGIGMAPGANLSDTHAIFEATHGTAPDIAGQG KANPSSLILSAVMMLEHLGWGEAAQAIVAAMNATIAAGEV TGDLAALRGDVPALSTTEFTAALIRRF Description Functional site 1) chain C residue 105 type sequence T description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 2) chain C residue 113 type sequence S description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 3) chain C residue 115 type sequence N description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 4) chain C residue 119 type sequence R description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 5) chain C residue 129 type sequence R description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 6) chain C residue 153 type sequence R description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 7) chain C residue 160 type sequence Y description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 8) chain C residue 320 type sequence D description BINDING SITE FOR RESIDUE FLC C 3201 source : AC3 9) chain C residue 230 type sequence K description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 10) chain C residue 232 type sequence N description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 11) chain C residue 233 type sequence I description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 12) chain C residue 296 type sequence D description BINDING SITE FOR RESIDUE FLC D 3301 source : AC4 13) chain C residue 37 type sequence I description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 14) chain C residue 100 type sequence K description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 15) chain C residue 102 type sequence P description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 16) chain C residue 103 type sequence L description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 17) chain C residue 104 type sequence E description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 18) chain C residue 105 type sequence T description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 19) chain C residue 115 type sequence N description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 20) chain C residue 333 type sequence I description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 21) chain C residue 349 type sequence E description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 22) chain C residue 351 type sequence T description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 23) chain C residue 352 type sequence H description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 24) chain C residue 353 type sequence G description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 25) chain C residue 354 type sequence T description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 26) chain C residue 355 type sequence A description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 27) chain C residue 357 type sequence D description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 28) chain C residue 364 type sequence A description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 29) chain C residue 365 type sequence N description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 30) chain C residue 405 type sequence D description BINDING SITE FOR RESIDUE NAD C 2201 source : AC7 31) chain C residue 232 type sequence N description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 32) chain C residue 294 type sequence I description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 33) chain C residue 297 type sequence N description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8 34) chain C residue 300 type sequence Q description BINDING SITE FOR RESIDUE NAD D 2301 source : AC8

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