eF-site ID 2d4v-A PDB Code 2d4v Chain A click to enlarge Title Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans Classification OXIDOREDUCTASE Compound isocitrate dehydrogenase Source Thiobacillus thiooxidans (Q8GAX0_THITH) Sequence A:  THIQKPATGSPLTLLNGVLQVPDQPIIPFIEGDGIGCDVT PAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQ YLPDETMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQDL DLYVCLRPVRYFEGTPSPMRHPEKVDMVIFRENSEDIYAG IEWPAGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVS TEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFR DWGYALAEREFAGRVFTWRQKAAISKAEGKAAGQKAEQQA IADGKLIIKDVIADNFLQQILLRPEDYSVVATLNLNGDYV SDALAAEVGGIGMAPGANLSDTHAIFEATHGTAPDIAGQG KANPSSLILSAVMMLEHLGWGEAAQAIVAAMNATIAAGEV TGDLAALRGDVPALSTTEFTAALIRRF Description Functional site 1) chain A residue 105 type sequence T description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 2) chain A residue 113 type sequence S description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 3) chain A residue 115 type sequence N description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 4) chain A residue 119 type sequence R description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 5) chain A residue 129 type sequence R description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 6) chain A residue 153 type sequence R description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 7) chain A residue 160 type sequence Y description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 8) chain A residue 320 type sequence D description BINDING SITE FOR RESIDUE FLC A 3001 source : AC1 9) chain A residue 230 type sequence K description BINDING SITE FOR RESIDUE FLC B 3101 source : AC2 10) chain A residue 232 type sequence N description BINDING SITE FOR RESIDUE FLC B 3101 source : AC2 11) chain A residue 233 type sequence I description BINDING SITE FOR RESIDUE FLC B 3101 source : AC2 12) chain A residue 37 type sequence I description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 13) chain A residue 100 type sequence K description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 14) chain A residue 102 type sequence P description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 15) chain A residue 103 type sequence L description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 16) chain A residue 104 type sequence E description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 17) chain A residue 105 type sequence T description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 18) chain A residue 115 type sequence N description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 19) chain A residue 333 type sequence I description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 20) chain A residue 349 type sequence E description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 21) chain A residue 351 type sequence T description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 22) chain A residue 352 type sequence H description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 23) chain A residue 353 type sequence G description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 24) chain A residue 354 type sequence T description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 25) chain A residue 355 type sequence A description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 26) chain A residue 357 type sequence D description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 27) chain A residue 364 type sequence A description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 28) chain A residue 365 type sequence N description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 29) chain A residue 405 type sequence D description BINDING SITE FOR RESIDUE NAD A 2001 source : AC5 30) chain A residue 232 type sequence N description BINDING SITE FOR RESIDUE NAD B 2101 source : AC6 31) chain A residue 294 type sequence I description BINDING SITE FOR RESIDUE NAD B 2101 source : AC6 32) chain A residue 297 type sequence N description BINDING SITE FOR RESIDUE NAD B 2101 source : AC6 33) chain A residue 300 type sequence Q description BINDING SITE FOR RESIDUE NAD B 2101 source : AC6 34) chain A residue 316-335 type prosite sequence NLNGDYVSDALAAEVGGIGM description IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLNGDYvSDalAaev.GGIGM source prosite : PS00470

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