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eF-site ID
|
2cyx-ABC |
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PDB Code
|
2cyx |
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Chain
|
A, B, C |
|
click to enlarge
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Title
|
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) |
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Classification
|
LIGASE |
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Compound
|
Ubiquitin-conjugating enzyme E2 G2 |
|
Source
|
null (UB2G2_HUMAN) |
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Sequence
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A: |
GSEFMAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFE
WEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCE
MFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSV
EKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAK
QIVQKSLGL
|
| B: |
GSEFMAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFE
WEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCE
MFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSV
EKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAK
QIVQKSLGL
|
| C: |
GSEFMAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFE
WEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCE
MFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSV
EKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAK
QIVQKSLGL
|
|
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
89 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
89 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
C |
| residue |
89 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
2 |
| type |
MOD_RES |
| sequence |
A
|
| description |
N-acetylalanine => ECO:0007744|PubMed:25944712
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
B |
| residue |
2 |
| type |
MOD_RES |
| sequence |
A
|
| description |
N-acetylalanine => ECO:0007744|PubMed:25944712
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
C |
| residue |
2 |
| type |
MOD_RES |
| sequence |
A
|
| description |
N-acetylalanine => ECO:0007744|PubMed:25944712
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
78-93 |
| type |
prosite |
| sequence |
FHPNIYPDGRVCISIL
|
| description |
UBC_1 Ubiquitin-conjugating (UBC) active site signature. FHPNIypd.GrVCIsiL
|
| source |
prosite : PS00183
|
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