eF-site ID 2cik-A PDB Code 2cik Chain A click to enlarge Title Insights Into Crossreactivity in Human Allorecognition: The Structure of HLA-B35011 Presenting an Epitope derived from Cytochrome P450. Classification IMMUNE SYSTEM/PEPTIDE Compound HLA CLASS I HISTOCOMPATIBILITY ANTIGEN B-35 ALPHA CHAIN Source null (2CIK) Sequence A:  GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDA ASPRTEPRAPWIEQEGPEYWDRNTQIFKTNTQTYRESLRN LRGYYNQSEAGSHIIQRMYGCDLGPDGRLLRGHDQSAYDG KDYIALNEDLSSWTAADTAAQITQRKWEAARVAEQLRAYL EGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRT FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP Description Functional site 1) chain A residue 6 type sequence R description BINDING SITE FOR RESIDUE GOL A1277 source : AC1 2) chain A residue 8 type sequence F description BINDING SITE FOR RESIDUE GOL A1277 source : AC1 3) chain A residue 29 type sequence D description BINDING SITE FOR RESIDUE GOL A1277 source : AC1 4) chain A residue 30 type sequence D description BINDING SITE FOR RESIDUE GOL A1277 source : AC1 5) chain A residue 206 type sequence L description BINDING SITE FOR RESIDUE GOL B1101 source : AC3 6) chain A residue 234 type sequence R description BINDING SITE FOR RESIDUE GOL B1101 source : AC3 7) chain A residue 242 type sequence Q description BINDING SITE FOR RESIDUE GOL B1101 source : AC3 8) chain A residue 84 type MOD_RES sequence Y description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 source Swiss-Prot : SWS_FT_FI1 9) chain A residue 143 type MOD_RES sequence T description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 146 type MOD_RES sequence K description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 152 type MOD_RES sequence V description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 159 type MOD_RES sequence Y description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 171 type MOD_RES sequence Y description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 257-263 type prosite sequence YTCHVQH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVQH source prosite : PS00290

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