|
|
eF-site ID
|
2c8n-E |
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PDB Code
|
2c8n |
|
Chain
|
E |
|
click to enlarge
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Title
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The Structure of a family 51 arabinofuranosidase, Araf51, from Clostridium thermocellum in complex with 1,3-linked arabinoside of xylobiose. |
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Classification
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HYDROLASE |
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Compound
|
ALPHA-L-ARABINOFURANOSIDASE |
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Source
|
(Q4CJG5_CLOTM) |
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Sequence
|
E: |
KARMTVDKDYKIAEIDKRIYGSFVEHLGRAVYDGLYQPGN
SKSDEDGFRKDVIELVKELNVPIIRYPGGNFVSNYFWEDG
VGPVEDRPRRLDLAWKSIEPNQVGINEFAKWCKKVNAEIM
MAVNLGTRGISDACNLLEYCNHPGGSKYSDMRIKHGVKEP
HNIKVWCLGNAMDGPWQVGHKTMDEYGRIAEETARAMKMI
DPSIELVACGSSSKDMPTFPQWEATVLDYAYDYVDYISLH
QYYGNKENDTADFLAKSDDLDDFIRSVIATCDYIKAKKRS
KKDIYLSFDEWNVWYHSNNEDANIMQNEPWRIAPPLLEDI
YTFEDALLVGLMLITLMKHADRIKIACLAQLINVIAPIVT
ERNGGAAWRQTIFYPFMHASKYGRGIVLQPVINSPLHDTS
KHEDVTDIESVAIYNEEKEEVTIFAVNRNIHEDIVLVSDV
RGMKDYRLLEHIVLEHQDLKIRNSVNGEEVYPKNSDKSSF
ILTSMLRRASWNVIRIG
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Description
|
|
Functional site
|
|
|
1)
|
chain |
E |
| residue |
352 |
| type |
SITE |
| sequence |
Q
|
| description |
Important for substrate recognition
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
2)
|
chain |
E |
| residue |
352 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
3)
|
chain |
E |
| residue |
172 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
4)
|
chain |
E |
| residue |
173 |
| type |
ACT_SITE |
| sequence |
A
|
| description |
Proton donor/acceptor => ECO:0000305|PubMed:16336192
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
E |
| residue |
292 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Nucleophile => ECO:0000269|PubMed:16336192
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
E |
| residue |
244 |
| type |
BINDING |
| sequence |
Y
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
E |
| residue |
292 |
| type |
BINDING |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
E |
| residue |
27 |
| type |
BINDING |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
9)
|
chain |
E |
| residue |
72 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
10)
|
chain |
E |
| residue |
296 |
| type |
SITE |
| sequence |
W
|
| description |
Important for substrate recognition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
|