eF-site ID 2c5v-H
PDB Code 2c5v
Chain H

click to enlarge
Title Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design
Classification CELL CYCLE
Compound CELL DIVISION PROTEIN KINASE 2
Source Homo sapiens (Human) (2C5V)
Sequence H:  AAXRSLIXX
Description (1)  CELL DIVISION PROTEIN KINASE 2 (E.C.2.7.1.37), CYCLIN A2, ALA-ALA-ABA-ARG-SER-LEU-ILE-PFF-NH2


Functional site

1) chain H
residue 506-507
type binding
ligand PFF: 4-FLUORO-L-PHENYLALANINE
sequence LI
description 4-FLUORO-L-PHENYLALANINE binding site
source pdb_hetatom : PFF_2c5v_H_508

2) chain H
residue 501-502
type binding
ligand ABA: ALPHA-AMINOBUTYRIC ACID
sequence AA
description ALPHA-AMINOBUTYRIC ACID binding site
source pdb_hetatom : ABA_2c5v_H_503

3) chain H
residue 504-505
type binding
ligand ABA: ALPHA-AMINOBUTYRIC ACID
sequence RS
description ALPHA-AMINOBUTYRIC ACID binding site
source pdb_hetatom : ABA_2c5v_H_503


Display surface

Download
Links