eF-site ID 2c5v-C PDB Code 2c5v Chain C click to enlarge Title Differential Binding Of Inhibitors To Active And Inactive Cdk2 Provides Insights For Drug Design Classification CELL CYCLE Compound CELL DIVISION PROTEIN KINASE 2 Source Homo sapiens (Human) (2C5V) Sequence C:  MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTE TEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVF EFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYT HEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRR ALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAA LAHPFFQDVTKPVPHL Description Functional site 1) chain C residue 10 type sequence I description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 2) chain C residue 31 type sequence A description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 3) chain C residue 33 type sequence K description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 4) chain C residue 80 type sequence F description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 5) chain C residue 81 type sequence E description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 6) chain C residue 83 type sequence L description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 7) chain C residue 84 type sequence H description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 8) chain C residue 85 type sequence Q description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 9) chain C residue 86 type sequence D description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 10) chain C residue 89 type sequence K description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 11) chain C residue 134 type sequence L description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 12) chain C residue 145 type sequence D description BINDING SITE FOR RESIDUE CK4 C1297 source : AC2 13) chain C residue 131 type catalytic sequence Q description Annotated By Reference To The Literature 1ir3 source CSA : CSA2 14) chain C residue 127 type catalytic sequence D description Annotated By Reference To The Literature 1ir3 source CSA : CSA2 15) chain C residue 127 type catalytic sequence D description Annotated By Reference To The Literature 1ir3 source CSA : CSA4 16) chain C residue 129 type catalytic sequence K description Annotated By Reference To The Literature 1ir3 source CSA : CSA4 17) chain C residue 127 type catalytic sequence D description Annotated By Reference To The Literature 1ir3 source CSA : CSA6 18) chain C residue 129 type catalytic sequence K description Annotated By Reference To The Literature 1ir3 source CSA : CSA6 19) chain C residue 165 type catalytic sequence T description Annotated By Reference To The Literature 1ir3 source CSA : CSA6 20) chain C residue 127 type catalytic sequence D description Annotated By Reference To The Literature 1ir3 source CSA : CSA8 21) chain C residue 129 type catalytic sequence K description Annotated By Reference To The Literature 1ir3 source CSA : CSA8 22) chain C residue 132 type catalytic sequence N description Annotated By Reference To The Literature 1ir3 source CSA : CSA8

Display surface Download Links