eF-site ID 2c53-A PDB Code 2c53 Chain A click to enlarge Title A comparative study of uracil DNA glycosylases from human and herpes simplex virus type 1 Classification HYDROLASE Compound URACIL DNA GLYCOSYLASE Source (UNG_HHV11) Sequence A:  LDWTTFRRVFLIDDAWRPLMEPELANPLTAHLLAEYNRRC QTEEVLPPREDVFSWTRYCTPDEVRVVIIGQNPYHHPGQA HGLAFSVRANVPPPPSLRNVLAAVKNCYPEARMSGHGCLE KWARDGVLLLNTTLTVKRGAAASHSRIGWDRFVGGVIRRL AARRPGLVFMLWGTHAQNAIRPDPRVHCVLKFSNPSPLSK VPFGTCQHFLVANRYLETRSISPIDWSV Description (1)  URACIL DNA GLYCOSYLASE (E.C.3.2.2.3) Functional site 1) chain A residue 86 type sequence G description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 2) chain A residue 87 type sequence Q description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 3) chain A residue 88 type sequence N description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 4) chain A residue 90 type sequence Y description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 5) chain A residue 100 type sequence A description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 6) chain A residue 101 type sequence F description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 7) chain A residue 112 type sequence S description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 8) chain A residue 147 type sequence N description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 9) chain A residue 212 type sequence S description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 10) chain A residue 213 type sequence P description BINDING SITE FOR RESIDUE DUR A 1245 source : AC1 11) chain A residue 214 type sequence L description BINDING SITE FOR RESIDUE GOL A 1246 source : AC2 12) chain A residue 216 type sequence K description BINDING SITE FOR RESIDUE GOL A 1246 source : AC2 13) chain A residue 115 type sequence N description BINDING SITE FOR RESIDUE GOL A 1247 source : AC3 14) chain A residue 218 type sequence P description BINDING SITE FOR RESIDUE GOL A 1247 source : AC3 15) chain A residue 219 type sequence F description BINDING SITE FOR RESIDUE GOL A 1247 source : AC3 16) chain A residue 220 type sequence G description BINDING SITE FOR RESIDUE GOL A 1247 source : AC3 17) chain A residue 197 type sequence R description BINDING SITE FOR RESIDUE GOL A 1248 source : AC4 18) chain A residue 199 type sequence D description BINDING SITE FOR RESIDUE GOL A 1248 source : AC4 19) chain A residue 200 type sequence P description BINDING SITE FOR RESIDUE GOL A 1248 source : AC4 20) chain A residue 181 type sequence P description BINDING SITE FOR RESIDUE GOL A 1249 source : AC5 21) chain A residue 235 type sequence R description BINDING SITE FOR RESIDUE GOL A 1249 source : AC5 22) chain A residue 237 type sequence I description BINDING SITE FOR RESIDUE GOL A 1249 source : AC5 23) chain A residue 88 type ACT_SITE sequence N description Proton acceptor => ECO:0000255|HAMAP-Rule:MF_04046 source Swiss-Prot : SWS_FT_FI1

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