|
|
eF-site ID
|
2c46-A |
|
PDB Code
|
2c46 |
|
Chain
|
A |
|
click to enlarge
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Title
|
CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase |
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Classification
|
TRANSFERASE |
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Compound
|
MRNA CAPPING ENZYME |
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Source
|
Homo sapiens (Human) (MCE1_HUMAN) |
|
|
Sequence
|
A: |
NLYFQSMAHNKIPPRWLNCPRRGQPVAGRFLPLKTMLGPR
YDSQVAEENRFHPSMLSNYLKSLKVKMGLLVDLTNTSRFY
DRNDIEKEGIKYIKLQCKGHGECPTTENTETFIRLCERFP
ELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQA
RPPGIYKGDYLKELFRRYGDIEEAPPPPLLPDWCFEDDED
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
124-134 |
| type |
prosite |
| sequence |
VHCTHGFNRTG
|
| description |
TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCthGfnRTG
|
| source |
prosite : PS00383
|
|
|
2)
|
chain |
A |
| residue |
126 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160
|
| source |
Swiss-Prot : SWS_FT_FI1
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