eF-site ID 2buj-B PDB Code 2buj Chain B click to enlarge Title Crystal structure of the human Serine-threonine Kinase 16 in complex with staurosporine Classification TRANSFERASE Compound SERINE/THREONINE-PROTEIN KINASE 16 Source (STK16_HUMAN) Sequence B:  ENLYFQGHMVIIDNKHYLFIQKLGEGGFSYVDLVEGLHDG HFYALKRILCHEQQDREEAQREADMHRLFNHPNILRLVAY CLREHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILW LLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDL GSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQ SHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVAL AVQNQLSPRHSSALWQLLNSMMTVDPHQRPHIPLLLSQLE ALQPPA Description (1)  SERINE/THREONINE-PROTEIN KINASE 16 (E.C.2.7.1.37) Functional site 1) chain B residue 30 type sequence G description BINDING SITE FOR RESIDUE CL B1298 source : AC2 2) chain B residue 32 type sequence S description BINDING SITE FOR RESIDUE CL B1298 source : AC2 3) chain B residue 24 type sequence Q description BINDING SITE FOR RESIDUE STU A1302 source : AC4 4) chain B residue 26 type sequence L description BINDING SITE FOR RESIDUE STU B1299 source : AC5 5) chain B residue 27 type sequence G description BINDING SITE FOR RESIDUE STU B1299 source : AC5 6) chain B residue 28 type sequence E description BINDING SITE FOR RESIDUE STU B1299 source : AC5 7) chain B residue 47 type sequence A description BINDING SITE FOR RESIDUE STU B1299 source : AC5 8) chain B residue 99 type sequence P description BINDING SITE FOR RESIDUE STU B1299 source : AC5 9) chain B residue 100 type sequence F description BINDING SITE FOR RESIDUE STU B1299 source : AC5 10) chain B residue 101 type sequence F description BINDING SITE FOR RESIDUE STU B1299 source : AC5 11) chain B residue 165 type sequence M description BINDING SITE FOR RESIDUE STU B1299 source : AC5 12) chain B residue 24 type sequence Q description BINDING SITE FOR RESIDUE STU B1300 source : AC6 13) chain B residue 26 type sequence L description BINDING SITE FOR RESIDUE STU B1300 source : AC6 14) chain B residue 45 type sequence F description BINDING SITE FOR RESIDUE STU B1300 source : AC6 15) chain B residue 100 type sequence F description BINDING SITE FOR RESIDUE STU B1300 source : AC6 16) chain B residue 102 type sequence K description BINDING SITE FOR RESIDUE STU B1300 source : AC6 17) chain B residue 103 type sequence R description BINDING SITE FOR RESIDUE STU B1300 source : AC6 18) chain B residue 104 type sequence G description BINDING SITE FOR RESIDUE STU B1300 source : AC6 19) chain B residue 149 type ACT_SITE sequence L description Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 27 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 21) chain B residue 50 type BINDING sequence R description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 22) chain B residue 186 type MOD_RES sequence L description Phosphothreonine; by autocatalysis => ECO:0000269|PubMed:18184589 source Swiss-Prot : SWS_FT_FI3 23) chain B residue 198 type MOD_RES sequence Y description Phosphoserine; by autocatalysis => ECO:0000269|PubMed:18184589 source Swiss-Prot : SWS_FT_FI4 24) chain B residue 199 type MOD_RES sequence R description Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:18184589 source Swiss-Prot : SWS_FT_FI5

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