eF-site ID 2bks-B PDB Code 2bks Chain B click to enlarge Title crystal structure of Renin-PF00074777 complex Classification HYDROLASE Compound Renin Source Homo sapiens (Human) (RENI_HUMAN) Sequence B:  SSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVP SSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGT VSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGV VGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSE NLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSV GSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKK RLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESY SSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRR NNRIGFALAR Description Functional site 1) chain B residue 13 type sequence T description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 2) chain B residue 14 type sequence Q description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 3) chain B residue 15 type sequence Y description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 4) chain B residue 33 type sequence D description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 5) chain B residue 35 type sequence G description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 6) chain B residue 40 type sequence W description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 7) chain B residue 42 type sequence P description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 8) chain B residue 56 type sequence H description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 9) chain B residue 78 type sequence Y description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 10) chain B residue 106 type sequence V description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 11) chain B residue 109 type sequence M description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 12) chain B residue 113 type sequence P description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 13) chain B residue 114 type sequence F description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 14) chain B residue 117 type sequence A description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 15) chain B residue 119 type sequence F description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 16) chain B residue 120 type sequence D description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 17) chain B residue 121 type sequence G description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 18) chain B residue 122 type sequence V description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 19) chain B residue 219 type sequence D description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 20) chain B residue 221 type sequence G description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 21) chain B residue 223 type sequence S description BINDING SITE FOR RESIDUE PZ1 B 401 source : AC1 22) chain B residue 33 type ACT_SITE sequence D description ACT_SITE => ECO:0000269|PubMed:20927107 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 219 type ACT_SITE sequence D description ACT_SITE => ECO:0000269|PubMed:20927107 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 70 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:2493678 source Swiss-Prot : SWS_FT_FI2

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