eF-site ID 2b8p-AB
PDB Code 2b8p
Chain A, B

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Title Crystal structure of Acanthamoeba polyphaga mimivirus NDK, the first viral nucleoside diphosphate kinase
Classification TRANSFERASE
Compound Probable nucleoside diphosphate kinase
Source null (NDK_MIMIV)
Sequence A:  YKKAGLQRTLVLIKPDAFERSLVAEIMGRIEKKNFKIVSM
KFWSKAPRNLIEQHYKEYFNDNCDFMVSGPIISIVYEGTD
AISKIRRLQGNILTPGTIRGDLANDIRENLIHASDSEDSA
VDEISIWFP
B:  GLQRTLVLIKPDAFERSLVAEIMGRIEKKNFKIVSMKFWS
KAPRNLIEQHYKEHSEQSYFNDNCDFMVSGPIISIVYEGT
DAISKIRRLQGNILTPGTIRGDLANDIRENLIHASDSEDS
AVDEISIWFP
Description


Functional site

1) chain A
residue 9
type
sequence K
description BINDING SITE FOR RESIDUE SO4 A 5000
source : AC1

2) chain A
residue 50
type
sequence Y
description BINDING SITE FOR RESIDUE SO4 A 5000
source : AC1

3) chain A
residue 86
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A 5000
source : AC1

4) chain A
residue 99
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A 5000
source : AC1

5) chain A
residue 109
type
sequence N
description BINDING SITE FOR RESIDUE SO4 A 5000
source : AC1

6) chain A
residue 112
type
sequence H
description BINDING SITE FOR RESIDUE SO4 A 5000
source : AC1

7) chain B
residue 9
type
sequence K
description BINDING SITE FOR RESIDUE SO4 B 5001
source : AC2

8) chain B
residue 50
type
sequence Y
description BINDING SITE FOR RESIDUE SO4 B 5001
source : AC2

9) chain B
residue 99
type
sequence R
description BINDING SITE FOR RESIDUE SO4 B 5001
source : AC2

10) chain B
residue 109
type
sequence N
description BINDING SITE FOR RESIDUE SO4 B 5001
source : AC2

11) chain B
residue 112
type
sequence H
description BINDING SITE FOR RESIDUE SO4 B 5001
source : AC2

12) chain A
residue 91
type
sequence N
description BINDING SITE FOR RESIDUE SO4 A 5002
source : AC3

13) chain A
residue 92
type
sequence I
description BINDING SITE FOR RESIDUE SO4 A 5002
source : AC3

14) chain A
residue 99
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A 5002
source : AC3

15) chain A
residue 106
type
sequence I
description BINDING SITE FOR RESIDUE SO4 A 5002
source : AC3

16) chain A
residue 107
type
sequence R
description BINDING SITE FOR RESIDUE SO4 B 5003
source : AC4

17) chain B
residue 53
type
sequence H
description BINDING SITE FOR RESIDUE SO4 B 5003
source : AC4

18) chain B
residue 56
type
sequence Q
description BINDING SITE FOR RESIDUE SO4 B 5003
source : AC4

19) chain B
residue 58
type
sequence Y
description BINDING SITE FOR RESIDUE SO4 B 5003
source : AC4

20) chain A
residue 109-117
type prosite
sequence NLIHASDSE
description NDPK Nucleoside diphosphate kinase (NDPK) active site signature. NliHASDSE
source prosite : PS00469

21) chain A
residue 112
type ACT_SITE
sequence H
description Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU10030
source Swiss-Prot : SWS_FT_FI1

22) chain B
residue 112
type ACT_SITE
sequence H
description Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU10030
source Swiss-Prot : SWS_FT_FI1

23) chain A
residue 9
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI2

24) chain A
residue 58
type BINDING
sequence Y
description
source Swiss-Prot : SWS_FT_FI2

25) chain A
residue 86
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

26) chain A
residue 99
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

27) chain A
residue 109
type BINDING
sequence N
description
source Swiss-Prot : SWS_FT_FI2

28) chain B
residue 9
type BINDING
sequence K
description
source Swiss-Prot : SWS_FT_FI2

29) chain B
residue 58
type BINDING
sequence Y
description
source Swiss-Prot : SWS_FT_FI2

30) chain B
residue 86
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

31) chain B
residue 99
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

32) chain B
residue 109
type BINDING
sequence N
description
source Swiss-Prot : SWS_FT_FI2


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