|
|
eF-site ID
|
2b8k-C |
|
PDB Code
|
2b8k |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
12-subunit RNA Polymerase II |
|
Classification
|
TRANSFERASE |
|
Compound
|
DNA-directed RNA polymerase II largest subunit |
|
Source
|
ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
|
Sequence
|
C: |
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIP
TLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEY
SRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVS
NLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKG
IAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWP
QSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQ
VVVRGIDTLQKKVASILLALTQMDQD
|
|
|
Description
|
(1) |
DNA-directed RNA polymerase II largest subunit (E.C.2.7.7.6), DNA-directed RNA polymerase II 140 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerase II 45 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerase II 32 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerase II 19 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit 9 (E.C.2.7.7.6), DNA-directed RNA polymerases I/II/III subunit 10 (E.C.2.7.7.6), DNA-directed RNA polymerase II 13.6 kDa polypeptide (E.C.2.7.7.6), DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide (E.C.2.7.7.6)
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
86 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 319
|
| source |
: AC4
|
|
|
2)
|
chain |
C |
| residue |
88 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 319
|
| source |
: AC4
|
|
|
3)
|
chain |
C |
| residue |
92 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 319
|
| source |
: AC4
|
|
|
4)
|
chain |
C |
| residue |
95 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE ZN C 319
|
| source |
: AC4
|
|
|
5)
|
chain |
C |
| residue |
31-71 |
| type |
prosite |
| sequence |
NSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLI
P
|
| description |
RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRvmiaeiptlAidsVevetNtTvlaDEfIAhRLGLIP
|
| source |
prosite : PS00446
|
|
|
|