eF-site ID 2b1v-B PDB Code 2b1v Chain B click to enlarge Title Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide Classification HORMONE/GROWTH FACTOR RECEPTOR Compound Estrogen receptor Source (NCOA2_HUMAN) Sequence B:  SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMG LLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLEXAWL EILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKXVEGMVEI FDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL AQLLLILSHIRHMSNKGMEHLYSMKXKNVVPLSDLLLEML DAHL Description Functional site 1) chain B residue 343 type sequence M description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 2) chain B residue 346 type sequence L description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 3) chain B residue 353 type sequence E description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 4) chain B residue 384 type sequence L description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 5) chain B residue 394 type sequence R description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 6) chain B residue 404 type sequence F description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 7) chain B residue 524 type sequence H description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 8) chain B residue 353 type BINDING sequence E description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 9) chain B residue 394 type BINDING sequence R description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 10) chain B residue 524 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 11) chain B residue 537 type MOD_RES sequence S description Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 source Swiss-Prot : SWS_FT_FI2 12) chain B residue 447 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

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