eF-site ID 2b1v-ABCD PDB Code 2b1v Chain A, B, C, D click to enlarge Title Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide Classification HORMONE/GROWTH FACTOR RECEPTOR Compound Estrogen receptor Source (NCOA2_HUMAN) Sequence A:  SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMG LLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLEXAWL EILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKXVEGMVEI FDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFEEK DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS HIRHMSNKGMEHLYSMKXKNVVPLSDLLLEMLDAHR B:  SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMG LLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLEXAWL EILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKXVEGMVEI FDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL AQLLLILSHIRHMSNKGMEHLYSMKXKNVVPLSDLLLEML DAHL C:  KILHRLLQD D:  KILHRLLQD Description Functional site 1) chain A residue 353 type sequence E description BINDING SITE FOR RESIDUE 458 A 201 source : AC1 2) chain A residue 384 type sequence L description BINDING SITE FOR RESIDUE 458 A 201 source : AC1 3) chain A residue 394 type sequence R description BINDING SITE FOR RESIDUE 458 A 201 source : AC1 4) chain A residue 404 type sequence F description BINDING SITE FOR RESIDUE 458 A 201 source : AC1 5) chain A residue 524 type sequence H description BINDING SITE FOR RESIDUE 458 A 201 source : AC1 6) chain A residue 525 type sequence L description BINDING SITE FOR RESIDUE 458 A 201 source : AC1 7) chain B residue 343 type sequence M description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 8) chain B residue 346 type sequence L description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 9) chain B residue 353 type sequence E description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 10) chain B residue 384 type sequence L description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 11) chain B residue 394 type sequence R description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 12) chain B residue 404 type sequence F description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 13) chain B residue 524 type sequence H description BINDING SITE FOR RESIDUE 458 B 202 source : AC2 14) chain A residue 353 type BINDING sequence E description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 15) chain A residue 394 type BINDING sequence R description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 16) chain A residue 524 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 17) chain B residue 353 type BINDING sequence E description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 18) chain B residue 394 type BINDING sequence R description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 19) chain B residue 524 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE source Swiss-Prot : SWS_FT_FI1 20) chain A residue 537 type MOD_RES sequence S description Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 source Swiss-Prot : SWS_FT_FI2 21) chain B residue 537 type MOD_RES sequence S description Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 source Swiss-Prot : SWS_FT_FI2 22) chain A residue 447 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 23) chain B residue 447 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links