|
|
eF-site ID
|
2b0u-A |
|
PDB Code
|
2b0u |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
The Structure of the Follistatin:Activin Complex |
|
Classification
|
SIGNALING PROTEIN |
|
Compound
|
Inhibin beta A chain |
|
Source
|
Homo sapiens (Human) (FST_HUMAN) |
|
|
Sequence
|
A: |
GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYC
EGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
|
|
|
Description
|
(1) |
The Structure of the Follistatin:Activin Complex
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
17 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE MLI A 401
|
| source |
: AC5
|
|
|
2)
|
chain |
A |
| residue |
21 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE MLI A 402
|
| source |
: AC6
|
|
|
3)
|
chain |
A |
| residue |
22 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE MLI A 402
|
| source |
: AC6
|
|
|
4)
|
chain |
A |
| residue |
32 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR RESIDUE MLI A 403
|
| source |
: AC7
|
|
|
5)
|
chain |
A |
| residue |
90 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE MLI A 403
|
| source |
: AC7
|
|
|
6)
|
chain |
A |
| residue |
29-44 |
| type |
prosite |
| sequence |
IIAPSGYHANYCEGEC
|
| description |
TGF_BETA_1 TGF-beta family signature. IiaPsgYhanyCeGeC
|
| source |
prosite : PS00250
|
|
|
|